从宏观到微观：胰腺多维度解剖学研究进展及精准临床应用

doi:10.13418/j.issn.1001-165x.2026.2.16

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中国临床解剖学杂志 ›› 2026, Vol. 44 ›› Issue (2) : 228-233. DOI: 10.13418/j.issn.1001-165x.2026.2.16

综述

从宏观到微观：胰腺多维度解剖学研究进展及精准临床应用

刘灏，刘兰涛，席世涵，于广海，毕伏龙，王灵站*

作者信息 +

From macro to micro: advances in multidimensional pancreatic anatomy research and precision clinical application

Liu Hao, Liu Lantao, Xi Shihan, Yu Guanghai, Bi Fulong, Wang Lingzhan*

Author information +

文章历史 +

摘要

胰腺解剖学研究正由静态描绘迈向动态、多维解析。宏观层面，对胰腺系膜与腹膜后筋膜平面的重新界定，正持续驱动精准外科的发展；微观层面，空间转录组学揭示了炎症与肿瘤背景下胰腺组织的细胞异质性与空间格局。影像学方面，光子计数CT与内镜超声的技术迭代提升了微小结构的可视化能力，结合AI实现病灶的自动分割与良恶性判别。技术应用上，增强现实与荧光导航加速了数字化模型与手术场景的无缝衔接。展望未来，多模态数据融合、AI的深度赋能、个体化解剖学以及三维类器官技术将进一步推动胰腺疾病的精准诊疗，为基础研究与临床实践提供新的视角与路径。

Abstract

Pancreatic anatomical research is shifting from static description to dynamic, multidimensional analysis. At the macroanatomical level, the redefinition of the pancreatic mesentery and retroperitoneal fascial planes continues to drive advances in precision surgery. At the microanatomical level, spatial transcriptomics reveals cellular heterogeneity and spatial architecture of the pancreas under inflammatory and tumor conditions. In imaging, iterative advances in photon-counting CT and endoscopic ultrasound enhance visualization of fine structures, while AI enables automated lesion segmentation and benign-malignant classification. In applied technology, augmented reality and fluorescence-guided navigation are accelerating the seamless integration of digital models with the operative field. Looking ahead, multimodal data fusion, deeper AI integration, individualized (patient specific) anatomy, and three-dimensional organoid technologies will further propel precision diagnosis and treatment of pancreatic diseases, offering new perspectives and avenues for both basic research and clinical practice.

导出引用

刘灏, 刘兰涛, 席世涵, 于广海, 毕伏龙, 王灵站. 从宏观到微观：胰腺多维度解剖学研究进展及精准临床应用[J]. 中国临床解剖学杂志. 2026, 44(2): 228-233 https://doi.org/10.13418/j.issn.1001-165x.2026.2.16

Liu Hao, Liu Lantao, Xi Shihan, Yu Guanghai, Bi Fulong, Wang Lingzhan. From macro to micro: advances in multidimensional pancreatic anatomy research and precision clinical application[J]. Chinese Journal of Clinical Anatomy. 2026, 44(2): 228-233 https://doi.org/10.13418/j.issn.1001-165x.2026.2.16

中图分类号： R322

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