Objective To investigate the effect of fetal isolated unilateral ventriculomegaly on the volume of brain parenchyma and its clinical value in fetal diagnosis and treatment. Methods Isolated unilateral ventriculomegaly confirmed by ultrasound underwent fetal brain examination at 1.5T MRI. The width of lateral ventricle, the thickness of adjacent lateral brain parenchyma, the volume of lateral ventricle and the volume of cerebral hemisphere were measured on the dilated side and the normal side, and the volume of brain parenchyma was calculated. The changes of the width of lateral ventricle with gestational age were followed up at an interval of 1 month. Results A total of 49 fetuses with isolated unilateral ventricular dilatation at 23-31 gestational weeks were finally included in the study. They were divided into three groups according to the degree of dilatation: 12 cases in the mild dilatation group, 27 cases in the moderate dilatation group and 10 cases in the severe dilatation group. The results of comparative study were as follows: ⑴ Compared with the normal side, the thickness of adjacent brain parenchyma on the dilated side decreased, and the volume of brain parenchyma was no significant difference; ⑵ There were differences in the width and volume of the dilated lateral ventricle and the volume of the cerebral hemisphere among the three groups (P<0.05), and there was no significant difference in the thickness and volume of the brain parenchyma on the dilated side. ⑶ The follow-up showed that the width of lateral ventricle gradually decreased in 76% in the mild and moderate dilation groups, and the abortion rate in the severe dilation group was 80%. Conclusions Isolated unilateral lateral ventricular dilatation has no effect on the volume of brain parenchyma, and the prognosis of fetuses with mild to moderate dilatation is good, which provides important imaging information for the evaluation, prognosis and intervention of fetuses with lateral ventricular dilatation.
Sun Shanshan, Tian Mimi, Zhao Peng, Cai Shuo, Yang Tao, Yang Yongqing, Ma Wenjing, Lin Xiangtao
. MRI study of the effect of isolated unilateral ventriculomegaly on the volume of brain parenchyma[J]. Chinese Journal of Clinical Anatomy, 2023
, 41(1)
: 15
-19
.
DOI: 10.13418/j.issn.1001-165x.2023.1.03
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