Objective To investigate the application effects of virtual bronchoscopic navigation (VBN) in thoracoscopic partial lobectomy and wedge resection, and analyze the impact on traumatic stress indicators. Methods A total of 322 patients with early-stage non-small cell lung cancer (NSCLC) who underwent thoracoscopic partial lobectomy or wedge resection at the hospital from January 2022 to December 2024 were selected. Based on the localization method, patients were divided into a VBN group (n=158) and a control group (n=164). The control group received CT-guided dye marker injection for localization, while the VBN group received VBN-assisted localization. Surgery-related indicators, stress indicators, inflammatory factors, pulmonary function, blood gas analysis indicators, and surgical complications were compared between the two groups. Results Compared with the control group, the VBN group showed reductions in the duration of surgery, intraoperative blood loss, thoracic drainage volume, thoracic drainage days, and postoperative hospital stay (P<0.05). Postoperative serum cortisol (Cor) and norepinephrine (NE) levels, and surgical stress index (SSI) in the VBN group were lower than those in the control group (P<0.05). The VBN group exhibited lower postoperative serum levels of interleukin-6 (IL-6), C-reactive protein (CRP), and eosinophil cationic protein (ECP) compared with the control group (P<0.05). The VBN group demonstrated higher postoperative peak expiratory flow (PEF), forced expiratory volume in one second to vital capacity ratio (FEV1%), tidal volume (TV) per kilogram, inspiratory-to-expiratory time (Ti/Te) ratio, time to peak tidal expiratory flow to expiratory time ratio (TPTEF/TE), and volume to peak expiratory flow to total expiratory volume ratio (VPEF/VE) than the control group (P<0.05). After surgery, the VBN group had higher PaO2 and SaO2 and lower PaCO2 compared with the control group (P<0.05). The total complication rate in the VBN group (3.80%) was lower than that in the control group (9.76%) (P<0.05). Conclusion Using VBN in thoracoscopic partial lobectomy and wedge resection can significantly shorten operation time, reduce intraoperative trauma, stress and inflammatory response, improve respiratory function, reduce complications, and promote recovery.
Key words
Virtual bronchoscopic navigation /
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Partial lobectomy /
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Wedge resection /
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Trauma /
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Stress
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