From macro to micro: advances in multidimensional pancreatic anatomy research and precision clinical application

doi:10.13418/j.issn.1001-165x.2026.2.16

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Chinese Journal of Clinical Anatomy ›› 2026, Vol. 44 ›› Issue (2) : 228-233. DOI: 10.13418/j.issn.1001-165x.2026.2.16

From macro to micro: advances in multidimensional pancreatic anatomy research and precision clinical application

Liu Hao, Liu Lantao, Xi Shihan, Yu Guanghai, Bi Fulong, Wang Lingzhan*

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Abstract

Pancreatic anatomical research is shifting from static description to dynamic, multidimensional analysis. At the macroanatomical level, the redefinition of the pancreatic mesentery and retroperitoneal fascial planes continues to drive advances in precision surgery. At the microanatomical level, spatial transcriptomics reveals cellular heterogeneity and spatial architecture of the pancreas under inflammatory and tumor conditions. In imaging, iterative advances in photon-counting CT and endoscopic ultrasound enhance visualization of fine structures, while AI enables automated lesion segmentation and benign-malignant classification. In applied technology, augmented reality and fluorescence-guided navigation are accelerating the seamless integration of digital models with the operative field. Looking ahead, multimodal data fusion, deeper AI integration, individualized (patient specific) anatomy, and three-dimensional organoid technologies will further propel precision diagnosis and treatment of pancreatic diseases, offering new perspectives and avenues for both basic research and clinical practice.

Key words

Pancreas / / / Anatomy / / / Imaging / / / Artificial intelligence / / / Endoscopic ultrasound / / / Spatial / transcriptomics / / / Precision medicine

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Liu Hao, Liu Lantao, Xi Shihan, Yu Guanghai, Bi Fulong, Wang Lingzhan. From macro to micro: advances in multidimensional pancreatic anatomy research and precision clinical application[J]. Chinese Journal of Clinical Anatomy. 2026, 44(2): 228-233 https://doi.org/10.13418/j.issn.1001-165x.2026.2.16

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