Analysis of the diagnostic value of anatomical casting in fetal persistent left superior vena cava malformation: a case series of five and literature review

Huang Ruiling, Wang Yu, Ai Haidong, Ou Hongping, Hu Yang, Lv Yang, Jia Yongmei

Chinese Journal of Clinical Anatomy ›› 2025, Vol. 43 ›› Issue (5) : 622-625.

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Chinese Journal of Clinical Anatomy ›› 2025, Vol. 43 ›› Issue (5) : 622-625. DOI: 10.13418/j.issn.1001-165x.2025.5.20

Analysis of the diagnostic value of anatomical casting in fetal persistent left superior vena cava malformation: a case series of five and literature review

  • Huang Ruiling1,2, Wang Yu1,3, Ai Haidong3,  Ou Hongping1,3, Hu Yang3, Lv Yang 4, Jia Yongmei1,3 *
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Abstract

This article reports on five cases of fetal persistent left superior vena cava (PLSVC) diagnosed through anatomical casting techniques. By utilizing an improved dental plaster-barium sulfate infusion method, three-dimensional cardiovascular casting models were created and validated against ultrasound imaging. The cases were between 22 to 30 weeks of gestation. Among them, three presented with the absence of the left brachiocephalic vein type of PLSVC, while two exhibited the bridging type, complicated by various anomalies such as double outlet right ventricle (four cases), pulmonary artery stenosis (three cases), and right aortic arch (two cases). The casting technique clearly illustrated the course of the PLSVC and its spatial relationships with intracardiac malformations, particularly revealing the “Y” shaped blood flow pathway characteristic of the bridging type PLSVC, which is often misinterpreted in routine ultrasound examinations. This research indicates that anatomical casting can accurately reconstruct complex cardiovascular structures, providing precise anatomical references for prenatal ultrasound, thereby enhancing the accuracy of prenatal diagnosis, and improving clinical decision-making quality.

Key words

Anatomical casting;  /   / Persistent left superior vena cava;  /   / Fetal congenital heart disease

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Huang Ruiling, Wang Yu, Ai Haidong, Ou Hongping, Hu Yang, Lv Yang, Jia Yongmei. Analysis of the diagnostic value of anatomical casting in fetal persistent left superior vena cava malformation: a case series of five and literature review[J]. Chinese Journal of Clinical Anatomy. 2025, 43(5): 622-625 https://doi.org/10.13418/j.issn.1001-165x.2025.5.20

References

[1] Galindo A, Gutiérrez-Larraya F, Escribano D, et al. Clinical significance of persistent left superior vena cava diagnosed in fetal life[J]. Ultrasound Obstet Gynecol, 2007,30(2): 152-161. DOI:10.1002/uog.4045.
[2]  Savu C, Petreanu C, Melinte A, et al. Persistent Left Superior Vena Cava-Accidental Finding[J]. In Vivo, 2020, 34(2):935-941. DOI: 10.1007/s12630-011-9510-x.
[3]  Berg C, Knüppel M, Geipel A, et al. Prenatal diagnosis of persistent left superior vena cava and its associated congenital anomalies[J]. Ultrasound Obstet Gynecol, 2006,27(3):274-280.DOI:10.1002/uog.2704.
[4]  Pasquini L, Belmar C, Seale A, et al. Prenatal diagnosis of absent right and persistent left superior vena cava[J]. Prenat Diagn, 2006,26(8):700-702. DOI: 10.1002/pd.1483.
[5]  肖慧彬, 林晓燕, 梁小勤, 等. 超声多切面连续扫查诊断胎儿永存左上腔静脉[J]. 中国医学影像技术, 2021, 37(1):95-99. DOI:1 0.13929/j.issn.1003-3289.2021.01.022.
       Xiao HB, Li XY, Liang XQ, et al. Ultrasound multi-section continuous scanning in diagnosis of fetal persistent left superior vena cava[J]. Chin J Med Imaging Technol, 2021, 37(1):95-99. DOI: 10.13929/j.issn. 1003-3289.2021.01.022.
[6]  秦朝彤, 侯小锋. 永存左上腔静脉患者心脏起搏导线植入技术[J]. 心血管病学进展, 2021, 42(12):1081-1084. DOI: 10.16806/j.cnki.issn.1004-3934.2021.12.006.
      Qin CT, Hou XF. Pacing Lead Implantation Techniques in Patients with Persistent Left Superior Vena Cava[J]. Adv Cardiovasc Dis, 2021, 42(12): 1081-1084. DOI: 10.16806/j.cnki.issn.1004-3934.2021.12.006.
[7]   练敏, 钟晓红, 周守兰, 等. 胎儿永存左上腔静脉的产前超声误诊原因及合并异常情况分析[J]. 中国超声医学杂志, 2022,38(10):1138-1141.DOI:10.3969/j.issn.1006-7795.2013.02.028.
      Lian M, Zhong XH, Zhou SL, et al. analysis of the causes of misdiagnosis by prenatal ultrasound and merge exceptions in fetuses with persistent left superior vena cava [J]. Chinese Ultrasound Med, 2022,38(10):1138-1141.DOI:10.3969/j.issn.1006-7795.2013.02.028. 
[8]  黄智军, 莫海云, 林丹红, 等. 左无名静脉在产前超声筛查胎儿上腔静脉先天变异中的价值[J]. 中国社区医师, 2023,39(4):115-116,120.DOI:10.3969/j.issn.1007-614x.2023.04.039.
      Huang ZJ, Mo HY, Lin DH, et al. Value of Left Innominate Vein in Prenatal Ultrasound Screening of Congenital Variation of Fetal Superior Vena Cava [J]. Chinese community doctors, 2023,39(4):115-116,120. DOI:10.3969/j.issn.1007-614x.2023.04.039.
[9]  聂志伟, 张军连, 石琳. 超声诊断胎儿永存左上腔静脉的临床应用价值[J]. 临床超声医学杂志, 2015, 17(11): 764-766. DOI: 10.16245/j.cnki.issn1008-6978.2015.11.018.
      Nie ZW, Zhang JL, Shi L. Application value of ultrasonography in diagnosis of fetal persistent left superior vena cava [J]. J Clin Ultrasound in Med, 2015, 17(11): 764-766. DOI: 10.16245/j.cnki.issn1008-6978.2015.11.018.
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