Experimental study on enhancing the quality of ex vivo placental tissue computed tomography angiography imaging using a self-setting barium sulfate composite material casting technology

doi:10.13418/j.issn.1001-165x.2025.5.19

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Chinese Journal of Clinical Anatomy ›› 2025, Vol. 43 ›› Issue (5) : 618-621. DOI: 10.13418/j.issn.1001-165x.2025.5.19

Experimental study on enhancing the quality of ex vivo placental tissue computed tomography angiography imaging using a self-setting barium sulfate composite material casting technology

Feng Ruizhi ¹, Hu yang¹, Chen Yuhua¹, Lv Yang², Wu You ³, Dai Jingxing⁴, Wu Zhixin⁵, Wang Yu¹*

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Abstract

Objective To optimize the imaging of computed tomography angiography (CTA) of ex vivo placental tissue by using a self-curing barium sulfate composite material for arteriovenous casting. Methods Normal full-term placentas were selected and randomly divided into two groups. Each group underwent CT scanning and 3D reconstruction using either traditional contrast agents or the self-curing barium sulfate composite material. Results The self-curing barium sulfate composite significantly enhanced the vascular filling and branch clarity in the CTA images. Blinded visual scoring demonstrated that the quality of CTA images obtained with the casting method surpassed those obtained with traditional methods, validating its effectiveness in ex vivo placental vascular studies. Conclusions The self-curing barium sulfate composite material shows significant advantages in ex vivo placental vascular research, improving the accuracy of placental pathology studies and clinical diagnoses. It provides new methodologies for diagnosing and treating related diseases.

Key words

Placenta; / Self-curing barium sulfate composite material; / Computed tomography angiography (CTA) imaging

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Feng Ruizhi , Hu yang, Chen Yuhua, Lv Yang, Wu You, Dai Jingxing, Wu Zhixin, Wang Yu. Experimental study on enhancing the quality of ex vivo placental tissue computed tomography angiography imaging using a self-setting barium sulfate composite material casting technology[J]. Chinese Journal of Clinical Anatomy. 2025, 43(5): 618-621 https://doi.org/10.13418/j.issn.1001-165x.2025.5.19

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