两种负荷条件下种植体骨结合率的比较研究
收稿日期: 2014-06-06
网络出版日期: 2014-12-04
基金资助
广东省科技计划项目（2010B010800023）
Comparative study of the implant osseointegration rate under two load conditions
Received date: 2014-06-06
Online published: 2014-12-04
目的 比较两种负荷条件下的种植体骨结合率。 方法 4只Beagle犬拔除一侧下颌4颗前磨牙，愈合8周后，在每只犬口内各植入4颗种植体。种植体植入10周后安装修复基台，其中近中2颗种植体基台无咬合接触作为对照组，远中2颗种植体通过加高咬合1mm获得过度负荷作为实验组。修复基台安装8周后处死取材，制作不脱钙骨磨片进行甲苯胺蓝染色后镜下骨形态计量学观察。 结果 骨形态计量学分析结果显示，安装修复基台8周后，实验组和对照组的骨-种植体结合率分别为(87.71±1.77)%，(83.15±2.47)%，实验组与对照组有显著差异（P<0.05）。 结论 过度负荷状态下，种植体的骨结合率提高。
黄杏香 , 张宇 , 向梅 , 谢畅 . 两种负荷条件下种植体骨结合率的比较研究[J]. 中国临床解剖学杂志, 2014 , 32(6) : 694 -697 . DOI: 10.13418/j.issn.1001-165x.2014
Objective To compare the implant osseointegration rate under two load conditions. Methods Four premolars on one side of the mandibular of 4 Beagle dogs were removed．After 8 weeks of the healing, 4 implants were implanted in the mouth of each dog. Prosthetic abutments were installed after 10 weeks of implant surgery，which were divided into 2 groups：the mesial two ones as the control group were free of any occlusal contact, the distal two ones as the experimental group were connected in supra-occlusal contact with the opposite teeth to get the excessive load. At 8 weeks, the dogs were sacrificed and all undecalcified hard tissue sections were stained with toluidine blue to perform bone histomorphometry analysis. Results Bone histomorphometry analysis showed that after installation of prosthetic abutments for 8 weeks, the implant osseointegration rate in the experimental group and the control group were (87.71±1.77) % and (83.15±2.47) %. There was a significant difference between the two groups. Conclusion Under excessive load conditions, the implant osseointegration rate was higher.
Key words： Implant; Overload; Osseointegration
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