收稿日期: 2013-09-10
网络出版日期: 2014-02-11
The preliminary study of the cerebellum medulla using Generalized Q-sampling Imaging
Received date: 2013-09-10
Online published: 2014-02-11
目的 应用基于GQI的弥散成像方法，对小脑的纤维束进行重建和显示，为小脑疾病的影像诊断进行解剖学和技术上的探索。 方法 首先把10例脑连接组项目的磁共振弥散数据导入DSI-studio软件，然后依次用该软件中的GQI（Generalized Q-sampling imaging）成像技术和流线算法（streamline algorithm）对与小脑有关的纤维束进行重建和显示。 结果 （1）在DSI-studio软件的二维和三维界面中显示了小脑三对脚的位置和交叉情况；（2）显示了小脑3对脚与脊髓、延髓、脑桥、中脑、端脑等的连接情况及其主要纤维成分。 结论 应用GQI技术可以对小脑白质进行重建和显示，为小脑疾病的影像学诊断提供技术和结构学上的帮助。
关键词： GQI; 脑连接组项目; DSI-studio软件; 小脑髓质
陈一勇 , 尹维刚 , 林荣 , 王守道 , 汪海清 , 李林 . 应用GQI技术对小脑髓质的初步研究[J]. 中国临床解剖学杂志, 2014 , 32(1) : 36 -40 . DOI: 10.13418/j.issn.1001-165x.2014.01.009
Objective To show the fibers that connected the cerebellum with brainstem, diencephalon and spinal cord using GQI. Methods We acquired high-resolution structural and diffusion MRI of 10 subjects from HCP. The tractography based on a GQI and streamline algorithm of the DSI-studio software was performed to reconstruct and show the fibers that linked the cerebellum with other parts of the CNS(Central Nervous System). Results (1) 2-dimensional and 3-dimensional positions and intersections of the superior (SCP), and middle (MCP) and inferior (ICP) cerebellar peduncles were showed using the DSI-studio software. (2) the main ingredients of the three peduncles of cerebellum which connected to the spinal cord, medulla oblongata, pons, midbrain, diencephalon were 3-dimensionally demonstrated. Conclusions The cerebellum medulla can reconstructed and displayed using GQI, providing a diagnostic tool for characterizing anatomical disruptions that occur in cerebellar diseases and for monitoring response to therapeutic interventions.
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