术前Hook-wire导丝定位的肺部磨玻璃结节临床病理特征分析

doi:10.13418/j.issn.1001-165x.2019.02.003

中国临床解剖学杂志 ›› 2019, Vol. 37 ›› Issue (2): 130-134.doi: 10.13418/j.issn.1001-165x.2019.02.003

术前Hook-wire导丝定位的肺部磨玻璃结节临床病理特征分析

王斌^{1, 2}，　张浩楠²，　高炜²，　张炜浩²，　徐彦²，　邢文阁²，　司同国²

1.天津市环湖医院肿瘤介入科，天津市脑血管与神经变性重点实验室，天津 300350；　2.天津医科大学肿瘤医院介入治疗科，
国家肿瘤临床医学研究中心，天津市“肿瘤防治”重点实验室，天津市恶性肿瘤临床医学研究中心，天津 300060

收稿日期:2018-11-01 出版日期:2019-03-25 发布日期:2019-04-29
通讯作者: 司同国，副主任医师，Tel:022-23340123，E-mail:drsitg@163.com
作者简介:王斌（1981-），在读硕士，研究方向：消融与免疫的基础与临床研究，Tel：18602278789，E-mail: huanhudrwang@163.com
基金资助:
国家自然基金项目（81471761，81501568）；天津市科技支撑计划重点项目（15ZCZDSY00890）

The postoperative clinicopathological characteristic of ground glass opacity localized by Hook-wire

WANG Bin^1,2, ZHANG Hao-nan², GAO Wei ², ZHANG Wei-hao ², XU Yan², XING Wen-ge², SI Tong-guo²

1. Department of Interventional Therapy of Tianjin Huanhu Hospital, Tianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Tianjin 300350; 2. Department of Interventional Therapy of Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China

Received:2018-11-01 Online:2019-03-25 Published:2019-04-29

摘要/Abstract

摘要：

目的　评价术前Hook-wire导丝定位的肺部磨玻璃结节（ground glass opacity，GGO）临床、影像特征与病理的关系。方法　收集83例GGO患者的临床、影像与术后病理资料，分析单纯磨玻璃病变（pure ground glass opacity，pGGO）与混合磨玻璃病变（mixed ground glass opacity，mGGO）的临床、影像特征与病理之间的联系。结果　83个病灶（pGGO 36例，mGGO 47例）均导丝定位成功，无严重并发症发生。对比分析发现mGGO中浸润性腺癌（IAC）患者比例明显高于pGGO（21.7% vs 7.2%，P=0.004）；而且mGGO组直径大于1 cm者IAC患者比例明显高于直径小于1 cm者（29.8% vs 8.4%，P=0.003）；年龄、性别、位置分布与病理类型无明显差别。结论　mGGO中IAC患者比例明显高于pGGO；结节直径≥1.0 cm的mGGO患者需采取积极的治疗方案。

关键词: , hook-wire导丝定位, 　磨玻璃结节, 　影像, 　病理

Abstract:

　Objective　To evaluate the relationship between the clinical and imaging features of the postoperative clinicpathological characteristic of ground glass opacity (GGO) localized by Hook-wire. Methods　Retrospective analysis was made in 83 cases of GGO patients with a diameter less than 2 cm in clinical data, imaging data and postoperative pathology, analysis of imaging findings of pure ground glass opacity (pGGO) and mixed ground glass opacity (mGGO). The relationship between clinical, imaging features and postoperative pathology of GGO was analyzed.　Results　A total of 83 lesions (36 cases of pGGO and 47 cases of mGGO) were successfully localized by Hook-wire with no severe complications. Comparative analysis found that the proportion of patients with invasive adenocarcinoma (IAC) in mGGO was significantly higher than that of pGGO (21.7% vs 7.2%, P=0.004). The proportion of IAC patients with diameter greater than 1 cm in mGGO group was significantly higher than that with diameter less than 1 cm (29.8% vs 8.4%, P=0.003). There was no significant difference in age, gender, location distribution and pathological type.　Conclusion　The proportion of IAC patients in mGGO is significantly higher than that of pGGO. mGGO patients with opacity diameter ≥1.0 cm need to adopt active therapeutic plan.

Key words: Hook-wire localization, 　Ground glass opacity, 　Imaging, 　Pathology

王斌,张浩楠,高炜,张炜浩,徐彦,邢文阁,司同国. 术前Hook-wire导丝定位的肺部磨玻璃结节临床病理特征分析[J]. 中国临床解剖学杂志, 2019, 37(2): 130-134.

WANG Bin, ZHANG Hao-nan, GAO Wei, ZHANG Wei-hao, XU Yan, XING Wen-ge, SI Tong-guo. The postoperative clinicopathological characteristic of ground glass opacity localized by Hook-wire[J]. Chinese Journal Of Clinical Anatomy, 2019, 37(2): 130-134.

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术前Hook-wire导丝定位的肺部磨玻璃结节临床病理特征分析

The postoperative clinicopathological characteristic of ground glass opacity localized by Hook-wire

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