甲状腺肿瘤手术中暴露并保护甲状旁腺的解剖与手术操作要点
Preservation of parathyroid gland during the resection of thyroid neoplasms: anatomy and operative procedure
目的 探讨甲状腺肿瘤手术中暴露并保护甲状旁腺的要点。 方法 对 2004年 1 月至2010 年 12 月 145例甲状腺弥漫性结节和甲状腺癌患者进行手术,分前、后3年两组,前3年组65例患者保留甲状腺后被膜,未寻找甲状旁腺;后3年组80例患者暴露并保护甲状旁腺,精细解剖观察被膜,尽量保存甲状旁腺的血供及完整性。术后进行动态监测血清钙变化,观察甲状旁腺的功能情况。 结果 在术中暴露并保护甲状旁腺后3年组中,术后甲状旁腺功能低下的机率较未寻找甲状旁腺前3年组患者明显降低,两组比较有统计学意义(P<0.05)。 结论 在甲状腺肿瘤手术中,暴露并保护好甲状旁腺,可有效降低术后甲状旁腺功能低下的发生率。
Objective To explore operational points for preserving parathyroid glands during the thyroid neoplasms surgery. Methods From Jan. 2004 to Dec. 2010, 145 cases of thyroid diffuse nodules and thyroid cancer underwent surgical therapy. Among them, 65 cases only preserved posterior capsule, but not presented parathyroid glands during the operation. However, another 80 cases were performed the liberation and preservation of parathyroid glands and its blood supply during the operation. Postoperative serum calcium level was monitored dynamicly, for evaluating the function of parathyroid glands. Results Postoperative incidence of hypoparathyroidism in patients exposing and preserving of parathyroid glands during the operation was significantly lower than that in patients with no special preserving of parathyroid glands(P<0.05). Conclusions During the thyroidectomy procedure, exposing and protecting the parathyroid gland can effectively decrease the incidence of postoperative hypoparathyroidism.
Thyroid neoplasms / Parathyroid glands / Surgical procedures
[1] Dionigi G, Bacuzzi A, Bertocchi V, et al. Prospectives andsurgical usefulness of perioperative parathyroid hormone assayin thyroid surgery
[J].Expert Rev Med Devices,2008,5(6):699-704.
[2] 黄国平,蔡铭智,陈培臻. 甲状腺癌术后低血钙症探讨
[J]. 实用医学杂志,2009,25(15):2501-2502.
[3] 曹利平,汪亮.甲状旁腺移植现状及趋势
[J].中国实用外科杂志,2008,2(83):227-229.
[4] 陈曦. 甲状腺手术中甲状旁腺功能的保护
[J]. 中国实用外科杂志,2010,30(10):895-897.
[5] 蔡秀军,邵雁.甲状腺术后低钙血症的预防和治疗
[J].临床外科杂志, 2004,12(10):591-592.
[6] Yun JS,Lee YS,Jung JJ,et al.The Zuckerkandl’s tubercle :auseful anatomical landmark for detecting both the recurrent la-ryngeal nervea ndt hes uperiorp arathyroidd uring thyroid surgery
[J].Endocr J,2008, 55(5):925-930.
[7] 刘岩岩,吴高松,马小鹏,等. Zuckerkandl结节:甲状腺手术中一个重要的解剖标志
[J].中华内分泌外科杂志,2010,4(2):90-91.
[8] 王宇.Ⅵ区清扫术的潜在风险-甲状旁腺意外切除
[J].中国癌症杂志,2009,19(1):48-51.
[9] 黄韬.甲状旁腺术中损伤的预防和处理
[J].中国实用外科杂志,2008,28(3):179-180.
[10]吴阶平,裘法祖.黄家驷外科学(中册)
[M].7 版.北京:人民卫生出版社, 2008:1138.
[11] Testini M, Rosato L, Avenia N, et al. The impact of single parathyroid gland autotransplantation during thyroid surgery on postoperative hypoparathyroidism: a multicenter study
[J]. Transplant Proc, 2007, 39(1):225-230.
[12]Roh JL, Park CI.Routine oral calcium and vitamin Dsupplements for prevention of hypocalcemia after totalthyroidectomy
[J].Am J Surg, 2006,192(5):675-678.
/
〈 |
|
〉 |