目的　探讨锥体束行程上无症状性腔隙性脑梗死大脑脚面积和FA值变化特点及临床意义。　方法　选取经核磁共振检查检确诊为锥体束行程上无症状性腔隙性脑梗死病人54例及正常人群组105例为研究对象，54例病人的大脑脚面积及FA值按梗死灶累及侧别，分为患侧组及健侧组并与对照组的左侧和右侧大脑脚的面积及FA值进行比较，同时比较了腔梗组和对照组的大脑脚面积及FA值的不对称比。　结果　无症状腔隙性脑梗死组双侧大脑脚面积小于对照组(左侧 F=17.104 ，P=0.000，右侧F=12.581,P=0.000),双大脑脚的FA值无差异(左侧P=0.894,右侧 P=0.968)。腔梗组双侧大脑脚面积及FA值无差异(分别为t=0.254 P=0.8,t=0.268 P=0.790)，腔梗组与对照组双大脑脚面积及FA值不对称比值无差异（分别为 t=0.114 P=0.67,t=1.463 P=0.175）。　结论　无症状性腔隙性脑梗死对于局限性脑梗死所引起Wallerian变性而导致的大脑脚面积及FA值的改变的无影响。

Objective　To research the change rules and clinical significance of area and fractional anisotropy (FA) in cerebral peduncles among patients with silent lacunar infarct in pyramidal tract  Methods: 54 patients with silent lacunar infarct in pyramidal tract diagnosed by MRI and 105 healthy adults were selected as study subjects. The cerebral peduncle area and FA of 54 patients were divided into two groups according to injured side of cerebral peduncle: injured side group and uninjured side group, the area and FA of two groups were compared with the control group, as well, the cerebral peduncle area and FA asymmentry ratio of lacunar infarct group was compared with that of the control group.　Results　The cerebral peduncle areas of 54 patients with silent lacunar infarct in pyramidal tract were smaller than that of control group(Left F=17.104 ，P=0.000，Right F=12.581,P=0.000). There was no difference of cerebral peduncle FA between lacunar infarct group and control group (Left P=0.894, Right P=0.968), and there was no difference of area and FA between left and right cerebral peduncle in lacunar infarct group (t=0.254 P=0.800,t=0.268 P=0.790). There was no difference of cerebral peduncle area and FA asymmentry ratio between observed group and control group (t=0.114 P=0.267,t=1.463 P=0.175.　Conclusions　The lesion of silent lucunar infarct in pyramidal tract can't lead to area and FA changes of cerebral peduncle in all, there is no affect on area and FA changes of cerebral peduncle caused by Wallerian degeneration after cerebral infarction.