目的：定量评价翼点锁孔入路对鞍区各解剖间隙的显微暴露。方法：在15例(30侧)经颈内动脉、椎动脉灌注红色乳胶的成人尸头上模拟经翼点锁孔入路，观察鞍区各间隙显微解剖结构，并在神经导航下量化可观察到的Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ间隙面积。结果：各间隙面积Ⅰ（22.23±2.12）mm²、Ⅱ（63.42±7.84）mm²、Ⅲ（64.96±5.43） mm²、Ⅳ（26±5.85） mm²、Ⅴ（16.64±2.97 ）mm²；可观察双侧视神经及视交叉、鞍隔、垂体柄及对侧颈内动脉、眼动脉、垂体上动脉及其分支；所有标本通过间隙Ⅱ、Ⅲ均可很好显露后交通动脉（PcoA）、脉络膜前动脉（AchA），清楚显示PcoA发出5-7支穿支，经下丘脑和后穿质穿入脑实质，从AchA发出6-7支小分支，分布于视束、钩回、脉络丛并穿入脑实质；大脑前、中动脉及分支，基底动脉分叉及大脑后动脉、小脑上动脉、动眼神经也可以良好暴露；调整显微镜视野还可观察动眼神经外侧间隙及海绵窦。结论：（1）翼点锁孔入路可良好显露鞍区各解剖间隙；（2）经Ⅱ、Ⅲ、Ⅴ间隙观察鞍上、鞍旁解剖结构较好；（3）更好显示后交通动脉、脉络膜前动脉起始和分支。

　　Objective: To explore quantitatively microsurgical anatomy in sellar region via the transpterional keyhole approach assisted by neuro-navigation. Methods: 15 silicone-injected adult cadaveric heads were dissected under operating microscope. The microstructures of sellar region were observed. The parameters of spaces ofⅠ,Ⅱ,Ⅲ,Ⅳ andⅤwere quantified by neuro-navigation. Results: The transpterional keyhole approach could expose five spaces very clearly. The areas of Ⅰ,Ⅱ,Ⅲ,Ⅳ and Ⅴspaces were （22.23±2.12）mm²,（63.42±7.84） mm², （64.96±5.43） mm²,（26±5.85 ）mm², and（16.64±2.97 ）mm² respectively.  Bilateral optic nerve, optic chiasma, sellae diaphragma and stalk hypophysial, and controlateral internal carotid artery, ophthalmic artery and superior hypophysial artery were well observed. Transpterional keyhole approach was more advantageous to view the Ⅱ、Ⅲ andⅤspace, especially  the  exposure for PcoA and AchA. The bifurcation of A1、M1 and the course of oculomotornerve in cistern could be well observed through the Ⅱ、Ⅲ andⅤ space. Conclusions: The transpterional keyhole approach could well expose the interspaces in sellar region, which is reliable to view sellar and parasellar structures  through the Ⅱ、Ⅲ andⅤspace, as well the exposure of the origin and branches of PcoA and AchA.