中国人群腰椎骺环发育的影像学特征

doi:10.13418/j.issn.1001-165x.2025.6.05

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中国临床解剖学杂志 ›› 2025, Vol. 43 ›› Issue (6) : 653-659. DOI: 10.13418/j.issn.1001-165x.2025.6.05

断层影像解剖

中国人群腰椎骺环发育的影像学特征

谢思远¹，李义凯^1,2，卢雄光³，曹俊杰¹，刘丹⁴*

作者信息 +

Imaging characteristics of lumbar vertebral ring apophysis development in the Chinese population

Xie Siyuan¹, Li Yikai¹,², Lu Xiongguang³, Cao Junjie¹, Liu Dan⁴*

Author information +

文章历史 +

摘要

目的描述中国人群腰椎骺环发育的影像学特征，分析不同年龄段和性别的骨化与融合模式，为青少年脊柱相关疾病的诊断与防治提供依据。方法回顾性分析2013年1月至2023年12月南方医科大学南方医院507例6岁~30岁健康个体的腰椎CT影像（男性252例，女性255例）。依据影像分级标准，由两名独立观察者评估腰椎骺环成熟度（S0~S4），并采用Spearman秩相关检验和组间比较，分析不同年龄、性别及解剖部位的发育差异。结果观察者间与观察者内一致性良好。腰椎骺环成熟度中位数与年龄呈显著正相关（r=0.97，P<0.001）。腰椎骺环的骨化集中于7~14岁，成熟起始于14岁后，成熟度中位数在18岁时达到S4阶段（完全成熟），但仍有38%的骺环未完全与椎体融合。女性较男性骺环发育更早。骨化及融合多始于后侧，前侧较晚完成。结论中国人群腰椎骺环发育表现出明显的年龄、性别及区域性差异。女性生长突增高峰（PHV）期间骺环未成熟与脊柱负荷骤增的矛盾，可能增加脊柱畸形的风险。本研究为青少年脊柱发育异常及损伤的预防与诊治提供了影像学依据。

Abstract

Objective To characterize the imaging features of lumbar vertebral epiphyseal ring development in the Chinese population, analyze ossification and fusion patterns in different age groups and genders, and provide evidence for the diagnosis and prevention of adolescent spinal disorders. Methods A retrospective analysis was conducted on lumbar CT scans of 507 healthy individuals (252 males, 255 females) aged 6 to 30 years from Nanfang hospital between January 2013 and December 2023. Based on imaging grading criteria, two independent observers assessed lumbar epiphyseal ring maturity (S0-S4). Spearman's rank correlation and intergroup comparisons were used to analyze developmental variations by age, gender, and anatomical regions. Results Inter- and intra-observer consistency was excellent. Median epiphyseal ring maturity significantly correlated with age (r=0.97, P<0.001). Ossification primarily occurred between 7 and 14 years, with maturation initiating after 14 years. Median maturity reached S4 (complete maturation) at 18 years, yet 38% of epiphyseal rings remained unfused. Females exhibited earlier developmental stages than males. Ossification and fusion predominantly began in posterior regions, with anterior regions completing later. Conclusions Lumbar ring apophysis development in the Chinese population demonstrates distinct age-, gender-, and region-specific variations. The contradiction between immature apophyses and abrupt spinal loading during peak height velocity (PHV) in females may elevate spinal deformity risks. This study provides imaging evidence for preventing and managing adolescent spinal developmental abnormalities and injuries.

导出引用

谢思远, 李义凯, 卢雄光, 曹俊杰, 刘丹. 中国人群腰椎骺环发育的影像学特征[J]. 中国临床解剖学杂志. 2025, 43(6): 653-659 https://doi.org/10.13418/j.issn.1001-165x.2025.6.05

Xie Siyuan, Li Yikai, Lu Xiongguang, Cao Junjie, Liu Dan. Imaging characteristics of lumbar vertebral ring apophysis development in the Chinese population[J]. Chinese Journal of Clinical Anatomy. 2025, 43(6): 653-659 https://doi.org/10.13418/j.issn.1001-165x.2025.6.05

中图分类号： R322.7

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