自凝硫酸钡复合材料铸型技术提升离体胎盘CTA影像质量的实验研究

doi:10.13418/j.issn.1001-165x.2025.5.19

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中国临床解剖学杂志 ›› 2025, Vol. 43 ›› Issue (5) : 618-621. DOI: 10.13418/j.issn.1001-165x.2025.5.19

技术方法

自凝硫酸钡复合材料铸型技术提升离体胎盘CTA影像质量的实验研究

冯睿智¹，胡阳¹，陈玉华¹，吕洋²，吴忧³，戴景兴⁴，伍芷欣⁵，王瑜 ¹*

作者信息 +

Experimental study on enhancing the quality of ex vivo placental tissue computed tomography angiography imaging using a self-setting barium sulfate composite material casting technology

Feng Ruizhi ¹, Hu yang¹, Chen Yuhua¹, Lv Yang², Wu You ³, Dai Jingxing⁴, Wu Zhixin⁵, Wang Yu¹*

Author information +

文章历史 +

摘要

目的使用自凝硫酸钡复合材料进行动静脉灌注铸型，以优化离体胎盘组织的计算机断层血管造影（CTA）影像质量。方法将60个正常、足月分娩的胎盘随机分为两组，分别使用传统造影剂和自凝硫酸钡复合材料灌注后进行CT扫描和3D重建。结果自凝硫酸钡复合材料显著提升了CTA血管充盈度和分支清晰度，铸型后的CTA影像质量优于传统方法。结论自凝硫酸钡复合材料在离体胎盘血管研究中表现出显著优势，有助于胎盘生理和病理研究，为相关疾病的诊治提供新的手段，提高临床诊断的准确性。

Abstract

Objective To optimize the imaging of computed tomography angiography (CTA) of ex vivo placental tissue by using a self-curing barium sulfate composite material for arteriovenous casting. Methods Normal full-term placentas were selected and randomly divided into two groups. Each group underwent CT scanning and 3D reconstruction using either traditional contrast agents or the self-curing barium sulfate composite material. Results The self-curing barium sulfate composite significantly enhanced the vascular filling and branch clarity in the CTA images. Blinded visual scoring demonstrated that the quality of CTA images obtained with the casting method surpassed those obtained with traditional methods, validating its effectiveness in ex vivo placental vascular studies. Conclusions The self-curing barium sulfate composite material shows significant advantages in ex vivo placental vascular research, improving the accuracy of placental pathology studies and clinical diagnoses. It provides new methodologies for diagnosing and treating related diseases.

导出引用

冯睿智, 胡阳, 陈玉华, 吕洋, 吴忧, 戴景兴, 伍芷欣, 王瑜. 自凝硫酸钡复合材料铸型技术提升离体胎盘CTA影像质量的实验研究[J]. 中国临床解剖学杂志. 2025, 43(5): 618-621 https://doi.org/10.13418/j.issn.1001-165x.2025.5.19

Feng Ruizhi , Hu yang, Chen Yuhua, Lv Yang, Wu You, Dai Jingxing, Wu Zhixin, Wang Yu. Experimental study on enhancing the quality of ex vivo placental tissue computed tomography angiography imaging using a self-setting barium sulfate composite material casting technology[J]. Chinese Journal of Clinical Anatomy. 2025, 43(5): 618-621 https://doi.org/10.13418/j.issn.1001-165x.2025.5.19

中图分类号： R817.4 R329.1

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基金

湖南省自然科学基金医卫行业联合基金（2025JJ81001）；中华国际医学交流基金会医药临床与成果转化基金-妇产领域疾病科研专项基金科研项目（Z-2014-08-2309-30）；湖北省科技厅面上项目指导性项目（2022CFC042）；襄阳市科技局医疗卫生领域科技计划重点项目（2021YL19）；襄阳市重点研发计划项目（2022YL44A）