Abstract: Objective    To evaluate the clinical effect of primary trigeminal neuralgia treatment by neuroendoscopy combined with microvascular decompression under microscope.    Methods    A retrospective analysis was made on 78 patients with primary trigeminal neuralgia treated by microvascular decompression, with 36 cases were treated by microvascular decompression under microscope (group A), and the other 42 cases were treated under neuroendoscopy  combined with microscope (group B).The discovery rate of offending vessels, complications rate, and therapeutic efficacy were compared in the two groups after treatment.    Results    The discovery rate of offending vessels in the group B (95.2%) was significantly higher than that of the group A (80.6%); The total effective rate of the group B (97.6%) was higher than that of the group A (83.3%). There were statistical differences in the discovery rate of offending vessels and total effective rate  in the two groups (P<0.05). There was no statistical difference in the postoperative complications between group A (30.6%) and group B (14.3%) (P>0.05).    Conclusions    The treatment of primary trigeminal neuralgia with neuroendoscopy combined with microvascular decompression microscope is of high clinical application value to improve the discovery rate of offending vessels and cure rate.

Key words: Primary trigeminal neuragia,  ,  ,  , Microvascular decompression,  ,  , Neuroendoscopy,  , Microscope