TVT与TVT-O不同位置治疗老年女性压力性尿失禁的有限元分析

李伟君, 周沂, 吴建辉, 陈丽华, 刘海英, 翟丽东

中国临床解剖学杂志 ›› 2025, Vol. 43 ›› Issue (1) : 76-81.

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中国临床解剖学杂志 ›› 2025, Vol. 43 ›› Issue (1) : 76-81. DOI: 10.13418/j.issn.1001-165x.2025.1.12
临床生物力学

TVT与TVT-O不同位置治疗老年女性压力性尿失禁的有限元分析

  • 李伟君1,    周沂1,    吴建辉2,    陈丽华3,    刘海英4,    翟丽东1*
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Finite element analysis of different positions of TVT and TVT-O in the treatment of stress urinary incontinence in elderly women

  • Li Weijun1, Zhou Yi1, Wu Jianhui2, Chen Lihua3, Liu Haiying4, Zhai Lidong1*
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摘要

目的    用有限元分析的方法模拟老年女性压力性尿失禁(Stress urinary incontience, SUI)常见吊带手术:经耻骨后无张力尿道吊带(Tension-free vaginal tape, TVT)和经闭孔无张力尿道吊带(Tension-free vaginal tape-obturator, TVT-O),评估它们在尿道不同位置的治疗效果。  方法   根据一名无盆底疾病女性的磁共振(MRI)图像构建盆腔几何模型。将老年阴道组织薄弱认定为组织刚度降低,施加腹压模拟valsalva运动并分别在尿道近端、中远端、远端放置TVT与TVT-O,得出力学数据。结果    尿道近端的吊带会导致α角与膀胱颈位移小于正常值。“漏斗”现象在吊带位于尿道近端与中远端时消失,位于尿道远端时依然存在;不同位置吊带与尿道之间的压强大小关系为:近端>中远端>远端。  结论     尿道近端(30%)的吊带容易导致尿道过紧,引起术后并发症;尿道远端(80%)的吊带治疗效果不佳;尿道中远端(60%)的吊带治疗效果好、术后并发症发生率低。尿道中远端放置TVT应该作为老年女性SUI手术的首选方法。

Abstract

Objective   To simulate common sling surgeries for stress urinary incontinence (SUI) in elderly women using finite element analysis methods: tension-free vaginal tape (TVT) and tension-free vaginal tape - obturator (TVT-O), and to evaluate their therapeutic effects at different positions of urethra. Methods    A pelvic geometry model was constructed based on magnetic resonance imaging (MRI) images of a woman without pelvic floor diseases. The thinning of elderly vaginal tissue was considered as a reduction in tissue stiffness. Abdominal pressure was applied to simulate valsalva maneuver, and TVT and TVT-O were placed at the proximal, mid-distal, and distal parts of urethra, respectively, to obtain mechanical data. Results    The sling at the proximal part of urethra would lead to the α-angle and bladder neck displacement less than normal values. The "funnel" phenomenon disappeared when the sling was located at the proximal and mid-distal parts of urethra, but still existed when located at the distal part; the pressure magnitude between the sling and urethra at different positions was: proximal > mid-distal > distal.   Conclusions   The sling at the proximal part of urethra (30%) is prone to cause excessive tightness of urethra, leading to postoperative complications, the sling at the distal part of urethra (80%) has poor therapeutic effect, the sling at the mid-distal part of urethra (60%) has a good therapeutic effect and a low incidence of postoperative complications. The placement of TVT at the mid-distal part of urethra should be the preferred surgical method for elderly women with SUI.

关键词

压力性尿失禁;  /   / TVT;  /   / TVT-O;  /   / 有限元分析;  /   / 生物力学

Key words

Stress urinary incontinence;  /   /  TVT;  /   /  TVT-O;  /   /  Finite element analysis;  /   / Biomechanics

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李伟君, 周沂, 吴建辉, 陈丽华, 刘海英, 翟丽东. TVT与TVT-O不同位置治疗老年女性压力性尿失禁的有限元分析[J]. 中国临床解剖学杂志. 2025, 43(1): 76-81 https://doi.org/10.13418/j.issn.1001-165x.2025.1.12
Li Weijun, Zhou Yi, Wu Jianhui, Chen Lihua, Liu Haiying, Zhai Lidong. Finite element analysis of different positions of TVT and TVT-O in the treatment of stress urinary incontinence in elderly women[J]. Chinese Journal of Clinical Anatomy. 2025, 43(1): 76-81 https://doi.org/10.13418/j.issn.1001-165x.2025.1.12
中图分类号: R318.01   

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基金

国家自然科学基金资助项目(31871212)

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