目的 报道应用股前外侧穿支皮瓣修复糖尿病足溃疡临床效果。 方法 回顾性总结分析2020年3月-2024年3月收治的35例采用游离股前外侧穿支皮瓣修复糖尿病足溃疡患者的病例资料,平均年龄62岁(45~70岁),创面大小5.0 cm×6.5 cm~24.0 cm×8.0 cm,创面位置:前足11例、足背9例、足底9例、足跟6例,所有患者均一期清创+VSD负压引流控制感染,二期采用股前外侧穿支皮瓣游离移植修复创面。 结果 所有患者受区血管均有不同程度的动脉硬化,3例皮瓣发生动脉危象,1例抢救成功,2例皮瓣完全坏死而截肢;1例皮瓣静脉危象及皮瓣下积液,部分坏死,换药治疗后创面愈合,其余31例皮瓣完全存活,存活率91.4%(32/35),保肢率94.3%(33/35);术后6个月,患者均能独自行走,足踝功能AOFAS评分73~95分,中位平均数87分;随访6~18个月,未见复发。 结论 股前外侧穿支皮瓣移植用于修复糖尿病足溃疡,可降低复发率和截肢率,并获得较好的功能及外观。
Abstract
Objectives To investigate the clinical application effect of the anterolateral thigh perforator flap for diabetic foot ulcer reconstruction. Methods A retrospective analysis was performed for the medical records of 35 patients from March 2020 to March 2024 who were treated with free anterolateral thigh perforator flap for diabetic foot ulcer reconstruction, the average age of the patients was 62 years old (45 to70 years), wound size was 5.0cm×6.5cm~24.0 cm×8.0cm. Wound location: 11 cases of forefoot, 9 cases of dorsum of feet, 9 cases of soles of feet, and 6 cases of heels. In all patients, infection was controlled by first-stage debridement and VSD negative pressure drainage. The wound was repaired by free transplantation of anterolateral thigh perforator flap in the second stage. Results All patients had varying degrees of arteriosclerosis in the donor site, 3 cases had arterial occluded with flap, 1 case was salvaged, and 2 cases had failed and amputation. One case had venous crisis, effusion under the flap, partial necrosis, wound healing after dressing change, and the rest of the flaps survived completely, with a survival rate of 91.4% (32/35) and the limb salvage rate of 94.3% (33/35). Six months after operation, all patients were able to walk independently, and the AOFAS score of foot and ankle function was 73-95 points, with a median average of 87 points. After 6-18 months follow-up, no recurrence was observed. Conclusions The anterolateral thigh perforator flap is used to repair diabetic foot ulcers, which can reduce the recurrence and amputation rates, and obtain satisfactory function and appearance.
关键词
股前外侧穿支皮瓣 /
糖尿病足 /
溃疡 /
负压式封闭引流 /
创面修复
Key words
Anterolateral thigh perforator flap /
Diabetic foot /
Ulceration /
Vacuum sealing drainage /
Wound repair
中图分类号:
R616.2
 
R625.9
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参考文献
[1]《多学科合作下糖尿病足防治专家共识版(2020版)》编写组. 多学科合作下糖尿病足防治专家共识(2020版)全版[J]. 中华烧伤杂志, 36(8): E1-E52. DOI:10.3760/cma.j.issn.1009-2587.2020.10.108.
[2] 刘小龙,苏福增,查天建,等. 新疆维吾尔自治区维吾尔族和汉族糖尿病患者发生糖尿病足溃疡的相关危险因素分析[J]. 中华烧伤杂志,2017, 33(8): 486-490.DOI: 10.3760/cma.j.issn.I009-2587.2017. 08.006.
[3] L Qing, Wu P, Yu F, et al. Use of dual-skin paddle anterolateral thigh perforator flaps in the reconstruction of complex defect of the foot and ankle[J]. J Plast Reconstr Aesthet Surg, 2018, 71(9): 1231-1238.DOI: 10.1016/j.bjps.2018.05.029.
[4] 刘双阳,梁久龙,何景涛,等. 股前外侧皮瓣治疗糖尿病足的临床疗效[J]. 中国美容整形外科杂志, 2019, 30(11): 662-663, 后插5.DOI: 10.3969/j.issn.1673-7040.2019.11.007
[5] D-G Armstrong, Boulton AJM, Bus S-A. Diabetic foot ulcers and their recurrence[J]. N Engl J Med, 2017, 376(24): 2367-2375.DOI: 10.1056/NEJMra1615439.
[6] 简扬,魏在荣,陈伟,等. 游离皮瓣在糖尿病足溃疡修复中的应用研究进展[J]. 中华烧伤与创面修复杂志, 2023, 39(4): 376-380.DOI: 10.3760/cma.j.cn501225-20221216-00539.
[7] Jin-Geun Kwon, Cho Min-Jeong, Pak Changsik-John, et al. A retrospective case series on free flap reconstruction for ischemic diabetic foot: The nutrient flap further explained[J]. Plast Reconstr Surg,2022, 149(6): 1452-1461.DOI: 10.1097/PRS.0000000000009132.
[8] 中华医学会显微外科学分会. MBCMA股前外侧皮瓣临床应用指南(2016征求意见稿)[J]. 中华显微外科杂志, 2016, 39(4): 313-317. DOI: 10.3760/cma.j.issn.1001-2036.2016.04.001.
[9] 海峡两岸医药卫生交流协会烧创伤暨组织修复专委会Cross-StraitsMedicineExchangeAssociation. 负压伤口疗法在糖尿病足创面治疗中的应用全国专家共识(2021版)[J]. 中华烧伤杂志, 2021, 36(6): 640-644. DOI:10.3760/cma.j.cn501120-20210107-00010.
[10]Frank Hsieh, Leow Osbert-Qi-Yao, Cheong Chon-Fok, et al. Musculoseptocutaneous perforator of anterolateral thigh flap: A Clinical Study[J]. Plast and Reconstr Surg, 2021, 147(1): 103e-110e. DOI: 10.1097/PRS.0000000000007471.
[11]E-J Fitzgerald O Connor, Vesely M, Holt P-J, et al. A systematic review of free tissue transfer in the management of non-traumatic lower extremity wounds in patients with diabetes[J]. Eur J Vasc Endovasc Surg, 2011, 41(3): 391-399.DOI: 10.1016/j.ejvs.2010.11.013.
[12]罗力生,高建华,陈林峰,等. 股前外侧皮瓣的解剖基础与临床应用[J]. 中华整形烧伤外科杂志, 1985, 01(2): 50-52.DOI:10.3760/cma.j.issn.1000-7806.1985.02.119.
[13]芮永军,唐举玉. 股前外侧皮瓣[M]. 北京市: 科学出版社, 2018: 72-121.
[14]Osman Kelahmetoglu, Mehdizade Turan, Unal Mustafa, et al. Free ALT Perforator Flap in Nonobese Patients: The recontouring of soft tissue defects around foot[J]. Indian J Orthop, 2021, 56(3): 445-451. DOI:10.1007/s43465-021-00518-y.
[15]J-P Hong. Reconstruction of the diabetic foot using the anterolateral thigh perforator flap[J]. Plast Reconstr Surg, 2006, 117(5): 1599-1608.DOI:10.1097/01.PRS.0000207057.16292.8f.
[16]J Boey, Yu L, Hui Z, et al. The limb salvage approach for the surgical management of necrotizing soft tissue infection[J]. Plast Reconstr Surg Glob Open,2023,11(8):e5207-e5209.DOI:10.1097/GOX.00000000000 05207.
[17]李小兵,刘洪均,杨超,等. 带阔筋膜游离股前外侧皮瓣修复糖尿病足溃疡伴骨外露[J]. 中国修复重建外科杂志, 2022, 36(1): 86-91.DOI:10.7507/1002-1892.202108110.
[18]窦雪娇,王海英,陈伟,等. 多巴酚丁胺对糖尿病足创面游离皮瓣修复术中血流灌注影响的前瞻性研究[J]. 中华烧伤与创面修复杂志, 2023, 39(8): 746-752.DOI:10.3760/cma.j.cn501225-20221220-00543.
基金
喀什地区科技局2021年科技计划项目(KS2021079)