目的 对我院游离股前外侧皮瓣坏死的影响因素进行总结,并对相关的影响因素进行探讨和分析。 方法 收集2014年6月至2024年6月我院手术的1260例游离股前外侧皮瓣的相关信息,对23个相关的影响因素进行分析,包括患者特点、术前因素、术中因素和术后因素。将这些影响因素与皮瓣坏死结果进行单因素分析和多变量Logistic回归分析。 结果 1260例游离股前外侧皮瓣成活1167例(92.6%),坏死93例(7.4%)。经统计学分析得出:静脉吻合数量、皮瓣感染、皮瓣下血肿、血管危象与游离股前外侧皮瓣的坏死密切相关。 结论 静脉血管吻合数(≥2)会增加血液回流,皮瓣更易成活;术中彻底清创、精确止血和充分的引流会减少皮瓣感染和血肿的发生,可以减少皮瓣坏死;术后及时发现动静脉血管危象并对应的处理,可以提高皮瓣成活率。
Abstract
Objective To summarize the influencing factors of free anterolateral thigh flap necrosis in our hospital, and to discuss and analyze the related influencing factors. Methods A total of 1260 free anterolateral femoral flaps operated in our hospital from June 2014 to June 2024 were collected, and 23 related influencing factors were analyzed, including patient characteristics, preoperative factors, intraoperative factors, postoperative factors. Univariate analysis and multivariate logistic regression analysis were performed on these influencing factors and the results of flap necrosis. Results 1260 free anterolateral thigh flaps survived in 1167 cases (92.6%) and necrotic in 93 cases (7.4%). Statistical analysis showed that the number of venous anastomosis, flap infection, subflap hematoma, vascular crisis were closely related to the necrosis of the free anterolateral femoral flap. Conclusions Venous vascular anastomosis (≥2) can increase blood return and make the flap more viable, and thorough debridement, precise hemostasis and adequate drainage during surgery can reduce the occurrence of flap infection and hematoma, reduce flap necrosis, and timely detection and treatment of arteriovenous crisis after surgery can improve the survival rate of flap.
关键词
游离股前外侧皮瓣 /
危险因素 /
坏死 /
回归分析
Key words
Free anterolateral thigh flap;  /
  /
Risk factor;  /
  /
Necrosis;  /
  /
Logistic regression analysis
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] 徐达传, 钟世镇, 罗力生. 股前外侧部皮瓣的解剖学—一个新的游离皮瓣供区[J]. 临床应用解剖学杂志, 1984, 2(3):158-160. DOI: 10.13418/j.issn.1001-165x.1984.03.012.
[2] Song YG, Chen GZ, Song YL. The free thigh flap: a new free flap concept based on the septocutaneous artery[J]. Br J Plast Surg, 1984, 37(2):149-159. DOI: 10.1016/0007-1226(84)90002-X.
[3] 中华医学会显微外科学分会. MBCMA股前外侧皮瓣临床应用指南(2016征求意见稿)[J]. 中华显微外科杂志, 2016, 39(4):313-317. DOI:10.3760/cma.j.issn.1001-2036.2016.04.001.
[4] Sanati-Mehrizy P, Massenburg BB, Rozehnal JM, et al. Risk factors leading to free flap failure: analysis from the national surgical quality improvement program database[J]. J Craniofac Surg, 2016, 27(8):1956-1964. DOI:10.1097/SCS.0000000000003026.
[5] 刘艳梅, 刘志峰, 张婷, 等. 游离皮瓣部分坏死的血液生化危险因素:多变量Logistic回归分析[J]. 中华手外科杂志, 2024, 40(2):140-144. DOI:10.3760/cma.j.cn311653-20240107-00005.
[6] Gong X, Cui JL, Jiang ZP, et al. Risk factors for pedicled flap necrosis in hand soft tissue reconstruction:a multivariate logistic regression analysis[J]. Anz J Surg, 2018, 88(3):E127-E131. DOI:10.1111/ans.13977.
[7] 周婷, 孙国文, 卢明星, 等.游离股前外侧皮瓣在颊癌根治术后缺损修复中的应用[J].中华整形外科杂志, 2017, 33(1):30-33. DOI:10.3760/cma.j.issn.1009-4598.2017.01.008.
[8] 彭城, 黎蕊, 黄东旭, 等. 游离皮瓣坏死的危险因素:多变量Logistic回归分析[J]. 中华显微外科杂志, 2017, 40(4):337-341. DOI:10.3760/cma.j.issn.1001-2036.2017.04.007.
[9] Liu Y, Zhao YF, Huang JT, et al. Analysis of 13 cases of venous compromise in 178 radial forearm free flaps for intraoral reconstruction[J]. Int J Oral Maxillofac Surg, 2012, 41(4):448-452. DOI:10.1016/j.ijom.2012.01.016.
[10] 徐磊, 巨积辉, 金乾衡, 等. 动脉和静脉完全换位在游离皮瓣动脉危象中的临床应用[J].中华显微外科杂志, 2018, 41(6):525-528. DOI:10.3760/cma.j.issn.1001-2036.2018.05.002.
[11]Patel SA, Pang JH, Natoli N, et al. Reliability of venous couplers for microanastomosis of the venae comitantes in free radial forearm flaps for head and neck reconstruction[J]. J Reconstr Microsurg, 2013, 29(7):433-436. DOI: 10.1055/s-0033-1343835.
[12]Sakurai Y, Sugimoto H, Yoshida K, et al. Superficial fibromatosis mimicking subcutaneous hematoma: an unusual and difficult diagnosis in a patient with mild hemophilia A[J]. Int J Hematol, 2007, 85(1):1-4. DOI:10.1532/IJH97.06084.
[13]Chabot JD, Patel CR, Hughes MA, et al. Nasoseptal flap necrosis: a rare complication of endoscopic endonasal surgery[J]. J Neurosurg, 2018, 128(5):1463-1472. DOI:10.3171/2017.2.JNS161582.
[14]Yu P, Chang DW, Miller MJ, et al. Analysis of 49 cases of flap compromise in 1310 free flaps for head and neck reconstruction[J]. Head Neck, 2009, 31(1):45-51. DOI:10.1002/hed.20927.
[15] Hill JB, Patel A, Del Corral GA, et al. Preoperative anemia predicts thrombosis and free flap failure in microvascular reconstruction[J]. Ann Plast Surg, 2012, 69(4):364-367. DOI:10.1097/SAP.0b013e31823ed606.
基金
无锡市“太湖人才”顶尖医学团队和“滨湖之光”医学专家团队项目支持