目的 为膝部腓总神经和胫神经病变的早期诊断提供新的影像学依据。 方法 选取不同年龄段的膝关节弥散张量成像正常者60例和单侧格林-巴利综合征住院患者20例，在工作站划分腓总神经和胫神经不同部位的感兴趣区，测量各向异性分数（fractional anisotropy，FA）值和表观弥散系数（apparent diffusion coefficient，ADC）值，生成纤维示踪图像，加以比较分析。 结果 膝部腓总神经和胫神经的左右侧、不同年龄段、不同部位的FA、ADC值均无统计学差异（P>0.05），合并处理得出腓总神经和胫神经的FA、ADC值分别为（0.65±0.05）、（1.04±0.12）×10-3mm2/s和（0.63±0.04）、（1.09±0.13）×10-3mm2/s。病变组膝部腓总神经和胫神经的FA、ADC值分别为（0.55±0.06）、1.26±0.19）×10-3mm2/s和（0.50±0.07）、（1.36±0.18）×10-3mm2/s，与正常组的差异均有统计学意义（P<0.05），病变组膝部腓总神经和胫神经的FA值均低于正常组，ADC值则高于正常组。 结论 弥散张量成像可以早期诊断膝部腓总神经和胫神经病变，纤维示踪成像可以显示病变的神经纤维形态变化，从而提高膝部腓总神经和胫神经病变早期的诊断率。
Abstract
Objective To provide new imaging basis for the early diagnosis of common peroneal nerve and tibial neuropathy in the knee. Methods Sixty patients with normal knee of different ages and twenty hospitalized patients with unilateral Guillain Barre syndrome were selected, the regions of interest of different parts of common peroneal nerve and tibial nerve were divided at the workstation. The fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values were measured and generated tractography imaging. Results There was no significant difference in FA and ADC values of common peroneal nerve and tibial nerve in the left and right sides, different age stages and different parts of knee (P>0.05). The FA and ADC values of common peroneal nerve and tibial nerve were (0.65±0.05), (1.04±0.12)×10-3mm2/s and (0.63±0.04), (1.09±0.13)×10-3mm2/s respectively by consolidation. The FA and ADC values of common peroneal nerve and tibial nerve of the knee in the lesion group were (0.55±0.06), (1.26±0.19)×10-3mm2/s and (0.50±0.07), (1.36±0.18)×10-3mm2/s respectively, which was satistically different from the normal group (P<0.05). The FA values of common peroneal nerve and tibial nerve of the knee in the lesion group were lower than those in the normal group, while the ADC values were higher than those in the normal group. Conclusions Diffusion tensor imaging can early diagnose the common peroneal nerve and tibial nerve lesion of the knee, and tractography imaging can show the morphological changes of nerve fibers, so as to improve the diagnosis rate of common peroneal nerve and tibial nerve lesion of the knee.
关键词
弥散张量成像 /
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膝部 /
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腓总神经 /
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胫神经 /
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纤维示踪成像 /
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临床应用
Key words
Diffusion tensor imaging /
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Knee /
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Common peroneal nerve /
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Tibial nerve /
Tractography imaging /
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Clinical application
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