目的 研究静脉窦内蛛网膜颗粒（arachnoid granulation，AG）随年龄变化的规律。 方法 按年龄分组收集360例核磁共振检查颅内未见异常的患者临床及影像资料，观察静脉窦内AG的分布、各年龄组AG的形状、大小和数量及同例患者AG形态随年龄变化情况。 结果 经MRI检查发现，AG最常出现的部位是横窦，其次是上矢状窦、直窦、窦汇，海绵窦未见；未成年组随着年龄的增加，AG的直径逐步增大，数量逐步增多，分叶型AG数量也增多；中青年组AG直径、数量随着年龄的增加而波动于某范围内，形状基本保持不变，能检测出AG的患者的例数及AG直径与未成年组相比均有统计学意义；老年组随着年龄的增加，AG直径减小，数量减少，分叶型AG数量也呈减少趋势，能检测出AG的患者例数及AG直径与中青年组相比均有统计学意义。 结论 不同年龄段人群的蛛网膜颗粒数量、大小及形状有所差异，这些变化可能与生长发育、衰老及脑脊液吸收调节有密切关系。
Abstract
Objective To study the relationship between the arachnoid granulation (AG) in dural sinus and age. Methods The clinical and imaging data of 360 patients with intracranial no abnormalities were collected according to the age. The distribution of AG in venous sinus and the shape, size, number and the changes of morphology in the same patients of AG in each age group were observed. Results MR examination showed that the most common site of AG was transverse sinus, followed by superior sagittal sinus, straight sinus, torcular, cavernous sinus. With the increasing of age in the juveniles patients group, the AG diameter became larger, the quantity and the number of lobulated of AG gradually increased. With the increasing of age in the middle-aged patients group, the diameter and number fluctuations in the fixed range, the shape remained basically unchanged. There were statistical difference in the number and diameter of patients who could detect AG between the juveniles group and the middle-aged group. With the increasing of age in the old-aged patients group, the AG diameter became small, number and the number of lobulated also reduced. There were statistical difference in the number and diameter of patients who could detect AG between the middle-aged group and the old-aged group. Conclusions The number, size and shape of the arachnoid granulation are variable in different age groups, and these changes may be closely related to growth and development, aging and regulation of cerebrospinal fluid reabsorption.
关键词
蛛网膜颗粒 /
核磁共振成像 /
年龄 /
脑脊液
Key words
Arachnoid granulation /
Magnetic resonance imaging /
Age /
Cerebrospinal fluid /
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基金
福建省科技计划引导性项目（2018Y0067）；福建省科技创新联合资金重大项目（2019Y9045）
京ICP备08002354号-3
