目的 分析腰椎峡部裂发生的危险因素,为腰椎峡部裂的预防和治疗提供参考依据。 方法 选取88例滑脱前期L5双侧峡部裂患者为研究对象,分析其体重指数、运动强度、腰椎发育情况及脊柱-骨盆结构相关参数;以88例体检正常者为对照组,进行统计学分析。 结果 研究组与对照组比较,相对代谢率、关节突关节椎弓根角、骨盆入射角、腰椎前凸角、峡部宽度、腰椎骶化、腰骶椎隐裂及家族史有统计学差异(P<0.05);以滑脱前期腰椎峡部裂为因变量的二分类logistic回归分析表明,相对代谢率、关节突关节椎弓根角、骨盆入射角及峡部宽度是腰椎峡部裂发生的危险因素。 结论 腰椎峡部裂的发生和多种因素相关,全面认识其危险因素,有助于降低其发生率,并预防进一步发展为滑脱。
Abstract
Objective To analyze the risk factors of lumbar spondylolysis, and provide reference for prevention and treatment of lumbar spondylolysis. Methods The body mass index, exercise intensity, spinal dysplasia and related spinal-pelvic structure parameters of 88 patients with slipping prophase L5 spondylolysis were analyzed. A control group with 88 normal volunteers were recruited in this study, and the corresponding indicators between two groups were statistically processed. Results There were statistical differences in relative metabolic rate, pedicle-facet angle, pelvic incidence angle, lumbar lordosis angle, lumbar isthmic width, lumbar sacralization, spina bifida occulta and family history between the slipping prophase lumbar spondylolisthesis group and the control group (P<0.05). Logistic regression analysis showed that relative metabolic rate, pedicle-facet angle, pelvic incidence angle and lumbar isthmic width were the risk factors for lumbar spondylolysis. Conclusion The occurrence of lumbar spondylolysis is related to many factors. A comprehensive understanding of its associated risk factors is helpful in reduction of its incidence and prevention its further development into slip.
关键词
腰椎峡部裂 /
滑脱前期 /
危险因素
Key words
Lumbar spondylolysis /
Slipping prophase /
Risk factors
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] Heminger RN. Spondylolysis and spondylolisthesis in children and adolescents[J]. J Bone Joint Surg Am, 1989, 71(7): 1098-1107.
[2] Savarirayan R, White SM, Goodman FR, et al. Broad phenotypic spectrum caused by an identical heterozygous CDMP-1 mutation in three unrelated families[J]. Am J Med Genet A, 2003, 117A(2): 136-142.
[3] Cai T, Yang L, Cai W, et al. Dysplastic spondylolysis is caused by mutations in the diastrophic dysplasia sulfate transporter gene[J]. Proc Natl Acad Sci U S A, 2015, 112(26): 8064-8069.
[4] Moke L, Debeer P, Moens P. Spondylolisthesis in twins: multifactorial etiology: a case report and review of the literature[J]. Spine(Phila Pa 1976), 2011, 36(11): E741-746.
[5] Vialle R, Ilharreborde B, Dauzac C, et al. Is there a sagittal imbalance of the spine in isthmic spondylolisthesis? A correlation study[J]. Eur Spine J, 2007, 16(10): 1641-1649.
[6] 贾俊峰, 赵杰, 陈志明, 等. 腰椎峡部裂型滑脱症矢状位参数分析[J]. 中国矫形外科杂志, 2007, 15(11): 850-852.
[7] 张继业, 朱青安, 姜欢畅, 等. 腰椎小关节不对称与小关节退变程度的关系及其临床意义[J]. 中国临床解剖学杂志, 2010, 28(6): 629-633.
[8] Elliott BC. Back injuries and the fast bowler in erieket[J]. J Sports Sci, 2000, 18(12): 983-991.
[9] Sakai T, Goda Y, Tezuka F, et al. Characteristics of lumbar spondylolysis in elementary school age children[J]. Eur Spine J, 2016, 25(2): 602-606.
[10]Leone A, Cianfoni A, Cerase A, et al. Lumbar spondylolysis: a review[J]. Skeletal Radiol, 2011, 40(6): 683-700.
[11]姜欢畅, 王吉兴, 尚平. 滑脱前期腰椎峡部裂屈伸运动中旋转稳定性分析[J]. 中国临床解剖学杂志, 2015, 33(1): 105-110.