CT预测肌层浸润性膀胱尿路上皮癌盆腔淋巴结转移的回顾性研究

doi:10.13418/j.issn.1001-165x.2019.04.014

中国临床解剖学杂志 ›› 2019, Vol. 37 ›› Issue (4): 431-435.doi: 10.13418/j.issn.1001-165x.2019.04.014

CT预测肌层浸润性膀胱尿路上皮癌盆腔淋巴结转移的回顾性研究

康丽丽¹，陈俊宏¹，　何雪婷¹，　李庭杰¹，　高飞²，　杨美^{1, 3}

1.重庆医科大学人体解剖学教研室；　2.重庆医科大学附属第一医院泌尿外科；　
3.重庆医科大学实验教学管理中心人体大体形态学实验室，重庆 400016

收稿日期:2019-01-21 出版日期:2019-07-25 发布日期:2019-08-01
通讯作者: 杨美，教授，硕士生导师，E-mail：yangmei19802002@126.com；高飞，副主任医师，副研究员，E-mail：gaofei667@163.com
作者简介:康丽丽（1992-），女，山西大同人，硕士，主要研究方向为膀胱癌的相关研究，Tel：17726639742，E-mail：1973484817@qq.com
基金资助:
国家自然科学基金（81672893）；重庆市教育委员会科学技术研究项目（KJQN201800428）

Retrospective study for CT predicting of pelvic lymph node metastasis in muscle-invasive bladder urothelial carcinoma

KANG Li-li¹, CHEN Jun-hong¹, HE Xue-ting¹, LI Ting-jie¹, GAO Fei², YANG Mei^1,3

1.Department of Human Anatomy, Chongqing Medical University; 2.Department of Urology, The First Affiliated Hospital of Chongqing Medical University; 3. Laboratory of Human Gross Morphology, Experimental Teaching Management center, Chongqing Medical University, Chongqing 400016, China

Received:2019-01-21 Online:2019-07-25 Published:2019-08-01

摘要/Abstract

摘要： 目的　探讨CT预测肌层浸润性膀胱尿路上皮癌（muscle-invasive bladder urothelial carcinoma，MIBUC）伴盆腔淋巴结转移的可行性。方法　回顾性分析接受根治性全膀胱切除术加盆腔淋巴结清扫术的40例MIBUC患者的临床和影像学资料，对比分析CT检查的盆腔淋巴结情况与病理诊断结果之间的相关性。结果　（1）以病理诊断结果为标准，CT检查发现MIBUC伴盆腔淋巴结转移的准确率为90%，灵敏度为75%，特异度为93.8%；（2）临床分期为T1、T2、T3、T4期的MIBUC患者，其盆腔淋巴结转移的发生率分别为0、9.1%、45.5%、100%。结论　（1）CT影像学检查可较好地预测MIBUC是否伴盆腔淋巴结转移；（2）随着MIBUC临床分期的进展，盆腔淋巴结转移的发生率相应增高（P<0.05）。

关键词: 膀胱癌, 　CT, 　淋巴结转移

Abstract: Objective　To evaluate the diagnostic accuracy of computed tomography (CT) for pelvic lymph node metastasis in muscle-invasive bladder urothelial carcinoma (MIBUC).　Methods　The present study retrospectively assessed the clinical and imaging characteristics of 40 MIBUC patients who underwent radical cystectomy and pelvic lymphadenectomy. The relationship between CT imaging characteristics and pathological examination for pelvic lymph node metastasis was assessed in MIBUC patients.　Results　(1) Compared to pathological diagnosis, CT imaging examination for pelvic lymph node metastasis had an accuracy of 90%, a sensitivity of 75%, and a specificity of 93.8%. (2) The pelvic lymph node metastasis rate increased along with more advanced tumor stage (T1, 0; T2, 9.1%; T3, 45.5%; T4, 100%).　Conclusions　(1) CT imaging characteristics are of great importance for evaluating pelvic lymph node metastasis in MIBUC patients. (2) The probability of metastatic pelvic lymph nodes significantly increases with more advanced T stages in MIBUC patients (P<0.05).

Key words: Bladder cancer; , , Computed Tomography; , , Pelvic lymph node metastasis

中图分类号:

R737.14

康丽丽, 陈俊宏, 何雪婷, 李庭杰, 高飞, 杨美. CT预测肌层浸润性膀胱尿路上皮癌盆腔淋巴结转移的回顾性研究[J]. 中国临床解剖学杂志, 2019, 37(4): 431-435.

KANG Li-li, CHEN Jun-hong, HE Xue-ting, LI Ting-jie, GAO Fei, YANG Mei. Retrospective study for CT predicting of pelvic lymph node metastasis in muscle-invasive bladder urothelial carcinoma[J]. Chinese Journal of Clinical Anatomy, 2019, 37(4): 431-435.

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CT预测肌层浸润性膀胱尿路上皮癌盆腔淋巴结转移的回顾性研究

Retrospective study for CT predicting of pelvic lymph node metastasis in muscle-invasive bladder urothelial carcinoma

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