目的　提高骨质不良骨标本的利用度，延长骨标本的使用寿命，避免传统清水漆涂刷保护的弊端。  方法　将干燥处理后的骨标本浸泡于HZ-806A/HZ-806B双组份环氧滴胶工作液中真空浸渍处理，并在甘油-乙醇保护液中浸泡初步固化，再经脱甘油后风干完全固化得到成品。最后分别从外观、解剖特征、物理性质等方面综合评估该方法对骨密质、骨松质的改善情况。  结果　经处理后在骨标本表面形成光滑薄漆膜，骨松质内空隙被固化后环氧滴胶填充，骨标本在硬度、韧性、安全性、色泽等方面较处理前有较大提升,平均增重率可达80.3%。  结论　真空浸渍技术应用于骨标本保护效果显著，尤其适用于骨质不良标本的保护，可作为骨标本保护的新技术手段。

Objective　This study aims to increase the accessibility and the life spans of bone specimens and to overcome the shortcomings of the polyurethane resin painting method that is widely used in bone specimen preservation.　Methods　Bone specimens of a male donor were first dried, and then immersed into the HZ-806A/HZ-806B two-component transparent epoxy resin for vacuum infusion. Then, the specimens were put into a mixed solution with a ethanol to glycerol ratio of 2:1 in weight for solidifying for 12 hours. After that, all specimens were moved into anhydrous ethanol to remove the glycerol component and then dried in the air. Last, the changes of the compact bone and the spongy bone were evaluated comprehensively with the aspects of appearance, anatomical features and physical properties.　Results　The cured transparent epoxy resin filled the space around bone trabecula in the spongy bone, and formed a hard, glossy, and transparent film on the surface of the bones, improving the hardness, toughness, safety, and color of the bone specimens. According to the statistical results, the average gaining weight rate of all specimens was 80.3%.　Conclusion　The vacuum infusion technique has a prominent advantage in bone processing, especially for the brittle bones that are hard to be utilized. Hopefully, this method will serve as a new common technical means for skeleton preservation.