目的　通过毛细血管灌注的方法，构建Wistar大鼠牙周炎模型的牙周毛细血管铸型，为牙周炎的微循环研究提供形态学方法。  方法　8周龄Wistar大鼠，从左心室的主动脉入口插管灌注颗粒状材料，皮肤肿胀发红灌注结束。灌注材料充分聚合24 h后，用腐蚀方法去除软组织。制成牙周炎的毛细血管铸型标本。S-3000N扫描式电子显微镜观察牙周毛细血管铸型。  结果　成功构建了牙周炎毛细血管铸型模型，在30、2000、4500倍扫描电镜下清晰地观察到了龈缘、龈沟及龈乳突等部位的毛细血管三维空间形态分布与走形。   结论　Wistar大鼠牙周炎的毛细血管铸型成功构建，为牙周炎微循环的研究提供了形态学方法，有助于从不同方面揭示牙周炎的各种病理变化。

Objective　To build the periodontal capillaries casting of Wistar rats by perfusion of their capillaries with microgranular materials, which provided a morphological method for study the microcirculation of periodontitis.　Methods　8-week-old Wistar rats were used to establish the animal model of periodontitis. Micropump was implanted from the inlet of the left ventricle of the aorta, and the liquid of the microgranular material was perfused to rely on the pressure of the pump. The swelling and redness of the skin indicated the success of perfusion. After the filling material was fully polymerized in the specimen for 24 hours, the soft tissue was removed by corrosion. The capillary cast specimens of periodontitis were  observed with the S-3000N scanning electron microscope (SEM).    Results  Under scanning electron microscope from 30, 2000, until 4500 times, the casting of the periodontal capillary, the three-dimensional space morphology and distribution of the capillaries of structures such as the gingival margin, gingival crevicular, gingival papillae  could be clearly viewed in the casting of the periodontal capillary.  Conclusion  The capillary cast can provide the morphological methods for periodontitis microcirculation research, and can be coordinated with the molecular biologic research of periodontitis, revealing various pathological changes of periodontitis from different aspects.