规则性肝切除与非规则性肝切除术后肝癌肝内复发状况比较分析

曾严; 张艳林; 张杰锋; 曾建挺; 张希; 何笑冬

doi:10.13418/j.issn.1001-165x.2018.01.020

中国临床解剖学杂志 ›› 2018, Vol. 36 ›› Issue (1) : 90-92. DOI: 10.13418/j.issn.1001-165x.2018.01.020

临床研究

规则性肝切除与非规则性肝切除术后肝癌肝内复发状况比较分析

曾严，　张艳林，　张杰锋，　曾建挺，　张希，　何笑冬

作者信息 +

Comparison of intrahepatic recurrence after regular hepatectomy and irregular hepatectomy in hepatocellular carcinoma patients

ZENG Yan, ZHANG Yan-lin, ZHANG Jie-feng, ZENG Jian-ting, ZHANG Xi, HE Xiao-dong

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文章历史 +

摘要

目的　分析规则性肝切除与非规则性肝切除术后肝癌肝内复发状况，旨在提高治疗效果。方法　选取2013年11月-2014年6月在我院住院治疗进行肝癌手术治疗的患者116例。将所有纳入研究患者随机分为规则性肝切除组和非规则性肝切除组，各58例。分别比较两组患者的术后肝功状况，以及术后1年复发率及患者生存率，并进行统计学分析。结果　规则肝切除组患者的血清ALB均高于非规则肝切除组，而TBLI、ALT和DBIL明显低于非规则肝切除组，t检验显示，两组间差异均具有统计学意义(P<0.05)。即规则肝切除组的肝功明显优于对照组。规则肝切除组患者的1年复发率明显低于非规则肝切除组，而1年生存率明显高于非规则肝切除组，两组在复发率和生存率间差异均具有统计学意义(P<0.05)。结论　规则性肝切除患者肝功能恢复好，肝内复发率低，生存率提高，可显著提高患者生活质量。

Abstract

Objective To analyze intrahepatic recurrence after regular hepatectomy and irregular hepatectomy in hepatocellular carcinoma patients, aiming at improving therapeutic effect. Methods 116 hepatocellular carcinoma patients surgically treated in our hospital from November 2013 to June 2014 were enrolled as subjects. All patients were randomly divided into regular hepatectomy and irregular hepatectomy group, 58 cases in each group. The liver function after six months, the recurrence rate after one year and the survival rate in two groups were compared.　Results　The serum albumin (ALB) in regular hepatectomy group was significantly higher, while TBIL, glutamic-pyruvic transaminase (ALT) and total bilirubin (DBIL) were significantly lower than that in irregular hepatectomy group at six months after surgery. T test showed that the differences between the two groups were all statistically significant (P<0.01). The 1-year recurrence rate in regular hepatectomy group was significantly lower than that in irregular hepatectomy group. 1-year survival rate in regular hepatectomy group were significantly higher (P<0.05). The differences between the two groups were statistically significant (P<0.05).　Conclusion　Regular hepatectomy treatment to hepatocellular carcinoma patients has better liver functional recovery, lower intrahepatic recurrence rate and higher survival rate. It can significantly improve the quality of life of patients.

导出引用

曾严,张艳林,张杰锋,曾建挺,张希,何笑冬. 规则性肝切除与非规则性肝切除术后肝癌肝内复发状况比较分析[J]. 中国临床解剖学杂志. 2018, 36(1): 90-92 https://doi.org/10.13418/j.issn.1001-165x.2018.01.020

ZENG Yan, ZHANG Yan-lin, ZHANG Jie-feng, ZENG Jian-ting, ZHANG Xi, HE Xiao-dong. Comparison of intrahepatic recurrence after regular hepatectomy and irregular hepatectomy in hepatocellular carcinoma patients[J]. Chinese Journal of Clinical Anatomy. 2018, 36(1): 90-92 https://doi.org/10.13418/j.issn.1001-165x.2018.01.020

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