目的　探讨胎肝血管三维模型的分割方法及其意义。  方法　采用分色和密度差金属造影剂对1例38周新鲜引产正常胎肝进行灌注并铸型，红色环氧树脂填充剂灌注腹主动脉（造影剂为氧化铅），蓝色环氧树脂填充剂灌注下腔静脉、静脉导管、肝左静脉及肝右静脉外侧支（造影剂为二氧化钛），紫色环氧树脂填充剂灌注肝中静脉（造影剂为氧化锌），绿色环氧树脂填充剂灌注肝右静脉内侧支（造影剂为氧化铅）。然后行128层螺旋CT薄层扫描和Mimics软件重建胎肝三维模型。  结果    构建胎肝血管三维模型形态逼真、立体感强。调整mimics阈值间距由大逐步变小，可以有效分割出肝中静脉、肝静脉系及肝固有动脉等血管，能清晰地显示肝内多血管走行及分布情况。   结论　不同密度金属造影剂灌注分割胎肝内多血管方法简便可行，能够为研究者对胎肝血管发生发展及其移植术的研究提供理想技术支持。

Objective　To explore the segmentation method of fetal hepatic vascular three-dimensional model and its significance.　Methods　One case of fresh induced labor normal fetal liver（38 week）was infused with color separation and density contrast metal contrast agent and then casted, red epoxy resin filler perfusion of abdominal aorta (contrast agent for lead oxide), blue epoxy resin filler perfusion of inferior vena cava, ductus venosus, left hepatic vein and lateral branch of right hepatic vein (contrast agent for titanium dioxide), purple epoxy resin filler perfusion of intermediate hepatic vein(contrast agent for zinc oxide), green epoxy resin filler perfusion of interior branch of right hepatic vein(contrast agent for lead oxide).the 128-slice spiral CT thin layer scanning and Mimics software were used to reconstruct three dimensional model of fetal liver.　Results　The three dimensional model of fetal hepatic vessels was constructed, which were clearly and solid. When the Mimics threshold spacing was progressively smaller, it can effectively segment the intermediate hepatic vein, the hepatic vein system and the hepatic proper artery, which can clearly show the course and distribution of the multiple vessels in fetal liver.　Conclusion　 It is simple and feasible to apply different density contrast agents to perfusion of multiple vessels in fetal liver, which can provide ideal technical support for the study of the development and transplantation of fetal hepatic vessels.