目的　探讨经髂骨开窗入路行骶髂关节感染手术的优势及可行性。  方法　2013-2015年,我院采用经髂骨开窗入路治疗5例骶髂关节感染患者，其中3例骶髂关节结核，另2例骶骨感染累及骶髂关节。依据CT测量骶髂关节在髂骨外板的投影数据，结合病灶的具体位置确定髂骨开窗位置，充分暴露病灶行清创手术。术后随访感染治疗效果及该入路对骶髂关节功能的影响。   结果　本组5例患者均获得大于12个月随访，所有患者骶髂关节感染消除，并恢复正常生活和工作。平片及CT检查未见骶髂关节脱位、不稳征象。  结论　经髂骨开窗入路显露充分，避免损伤关节周围韧带及前侧血管、神经等重要结构，减少对关节稳定性影响，手术风险小。与经典的前、后侧入路相比优势明显，可以作为骶髂关节手术入路的新选择。

Objective　To investigate the advantage and the feasibility of transiliac approach in the sacroiliac joint surgery.　Methods　From 2013 to 2015, totally 5 cases of sacroiliac joint infection (3 cases of sacroiliac joint tuberculosis, 2 cases of sacral infection related sacroiliac joint ) were treated by transiliac approach. The fenestration position was determined through the projection data of sacroiliac joint on the outer table of ilium by CT scanning and the location of the lesion. Then infection debridement was performed. The effect of anti-infective therapy and the influence of transiliac approach in sacroiliac joint function were followed up.　Results　All 5 patients had a follow-up of more than 12 months. The infection was eliminated in all patients who had returned to normal life and work. The X-ray and CT of pelvis showed no dislocation and unstable signs in the sacroiliac joint.　Conclusion　The transiliac approach can expose completely, avoid injury of joint ligaments and anterior vascular, nerve and other important structures. It also can reduce the effect on joint stability and have a low risk of operation. Compared with the classic anterior and posterior approach, the transiliac approach has obvious advantages and can be used as a new choice for the operation of sacroiliac joint.