基于2D/3D配准技术测量颈椎间孔形态学的精度研究
The precision of the 2D/3D registration techniques in measuring the cervical intervertebral foramen morphology
目的 探讨基于2D/3D配准技术测量离体颈椎标本椎间孔形态学的精度。 方法 获取16具颈椎离体标本的螺旋CT影像,通过三维重建获得相应标本的三维模型。然后改变标本的体位,再次行CT扫描并分别拍摄各具离体标本正侧位X线平片,采用2D/3D图像配准技术还原拍摄平片时颈椎的三维位置。利用Rapidform XOR3软件测量配准前与配准后C2/3至C6/7双侧的椎间孔面积、前后径和上下径。 结果 共测得椎间孔的面积、前后径和上下径各158个,经配对样本t检验,配准后椎间孔的面积、前后径、上下径与配准前相比较,结果无显著性差异(P>0.05);椎间孔面积的准确度为96.77%、精确度为(1.27±1.16)mm2,前后径的准确度为94.35%、精确度为(0.30±0.27)mm,上下径的准确度为96.14%、精确度为(0.32±0.28)mm。 结论 应用2D/3D配准技术测量颈椎间孔的形态学参数具有较高的准确度和精确度。
Objective To investigate the 2D/3D registration techniques in measurement accuracy of cervical intervertebral foramen morphology in specimens. Method Spiral CT images from 16 cervical specimens were collected to obtain a three-dimensional model through three-dimensional reconstruction. CT scan and lateral radiography with each isolated specimens after changed the position of the specimen were performed. 2D/3D image registration techniques were used to restore the cervical spine’s three-dimensional position where we had taken the X-rays. The bilateral foramen area, anteroposterior diameter and vertical diameter from C2/3 to C6/7 before and after registration were measured using Rapidform XOR3. Results The number of the foramen area, anteroposterior diameter and vertical diameter were measured were 158. Compared with the pre-registration, the registration area of the intervertebral foramen, anteroposterior diameter, and vertical diameter showed no significant difference (P>0.05) by paired samples t-test. The accuracy of the intervertebral foramen area was 96.77%, with a precision of (1.27±1.16) mm2, the accuracy of the anteroposterior diameter was 94.35% with a precision of (0.30±0.27) mm, the diameter of the upper and lower accurate degree was 96.14% with a precision of (0.32±0.28) mm. Conclusion Application of 2D/3D registration techniques to measure cervical intervertebral morphological parameters was high in accuracy and precision.
Cervical spine / Intervertebral foramen / 2D/3D registration
[1] 罗久伟,苏衍峰. 颈椎椎间孔大小与脊神经根型颈椎病的关系研究[J]. 中国医学影像技术, 2009, 25(z1):204-205.
[2] 潘福琼. 颈椎病的病因、诊断及治疗进展[J]. 现代康复, 2001, 5(8):86-87.
[3] Lubelski D, Derakhshan A, Nowacki AS, et al. Predicting C5 palsy via the use of preoperative anatomic measurements[J]. Spine J, 2014, 14(9):1895-1901.
[4] 叶强, 李鉴轶, 李鹏, 等. 利用2D/3D配准技术开展直立位颈椎椎间孔形态学测量的可行性研究[J]. 中国临床解剖学杂志, 2015, 33(3):288-290.
[5] Inufusa A, An HS, Lim TH, et al. Anatomic changes of the spinal canal and intervertebral foramen associated with flexion-extension movement[J]. Spine (Phila Pa 1976), 1996, 21(21):2412-2420.
[6] 余情,李泽兵. 颈椎间孔形态及颈椎间孔狭窄的研究进展[J]. 中华物理医学与康复杂志, 2002, 24(9):573-575.
[7] 郭强,杨正刚. 青年型颈椎病的X线、CT、MR诊断价值分析[J]. 西部医学, 2008, 20(2):375, 377.
[8] Bullitt E, Liu A, Aylward S R, et al. Registration of 3D cerebral vessels with 2D digital angiograms: clinical evaluation[J]. Acad Radiol, 1999, 6(9):539-546.
[9] Yamazaki T, Watanabe T, Nakajima Y, et al. Improvement of depth position in 2-D/3-D registration of knee implants using single-plane fluoroscopy[J]. IEEE Trans Med Imaging, 2004, 23(5):602-612.
[10] 张翼,王满宁,宋志坚. 脊柱手术导航中分步式2D/3D图像配准方法[J]. 计算机辅助设计与图形学学报, 2007,19(9):1154-1158.
[11] 马广栋,洪莉,王亮和. 2D/3D影像配准在鼻咽癌放疗中的应用[J]. 中国医疗设备,2013, (10):115-116.
[12] 李凭跃,尹庆水,黄华扬,等. 基于2D/3D配准技术的正常膝关节运动还原在体稳定性参数研究[J]. 中国临床解剖学杂志,2010, 28(5):571-574.
[13] Tomazevic D, Likar B, Slivnik T, et al. 3-D/2-D registration of CT and MR to X-ray images[J]. IEEE Trans Med Imaging, 2003, 22(11):1407-1416.
[14] Wang S, Passias P, Li G, et al. Measurement of vertebral kinematics using noninvasive image matching method-validation and application[J]. Spine (Phila Pa 1976),2008,33(11):E355-E361.
[15] Wang S, Xia Q, Passias P, et al. Measurement of geometric deformation of lumbar intervertebral discs under in-vivo weightbearing condition[J]. J Biomech,2009,42(6):705-711.
[16] Zhong W, Driscoll S J, Tsai T Y, et al. In vivo dynamic changes of dimensions in the lumbar intervertebral foramen[J]. Spine J,2015,15(7):1653-1659.
广东省省级科技计划项目(2012B091100314,2014A020212200,2015A040404022,2015B010125006,2015B010125005
/
〈 |
|
〉 |