目的　利用MRI三维重建及旋转分割方法对膝骨性关节炎患者及正常人半月板的形态及位置进行定量测量并对比分析，探讨膝骨性关节炎患者半月板的形态、位置变化及其临床意义。  方法　选取2013年1月-2014年2月在我院诊治的膝骨性关节炎II、III级患者20例（共20膝）作为关节炎组，另选择年龄、性别、体重指数相匹配的正常人10例（共10膝）作为正常组。所有研究对象先行MRI 3D薄层扫描，后行三维重建及旋转分割，在分割后的图像上对半月板进行定量测量，以半月板整体宽度、半月板覆盖胫骨平台宽度和半月板厚度作为量化指标进行两组间对比研究。  结果　内侧半月板整体宽度在所有方向上两组间差异无统计学意义；覆盖胫骨平台宽度从60°~120°位关节炎组明显变小，两组间差异具有统计学意义；厚度在60°~130°位关节炎组明显变厚，两组间差异具有统计学意义。外侧半月板整体宽度及覆盖胫骨平台宽度在10°~50°及140°~170°位关节炎组显著变宽，两组间差异具有统计学意义；厚度在120°~170°位关节炎组明显变厚，两组间差异有统计学意义。   结论　本研究为临床上半月板的MRI检查提供了一个新的方法和思路；通过测量发现膝骨性关节炎患者半月板的形状、位置与正常人相比发生了明显的变化，且这种变化同膝关节骨性关节炎具有一定相关性。

Objective　Using the magnetic resonance imaging 3D reconstruction and rotation  segmentation methods to measure the meniscuses of patients with knee osteoarthritis and normal adults, and the morphological and positional changes of the meniscus on patients with osteoarthritis and its clinical significance were explored.　Methods　20 cases of patients with knee osteoarthritis (II, III grade) involving 20 knee joints were selected from our hospital as osteoarthritis group between January 2013 to February 2014. The other,10 cases of normal people, involving 10 knee joints were chosen as a normal group. The age, sex, body mass index were matched between the two groups. Firstly, all subjects were scanned using thin slices of MRI, and the images obtained were then transferred for the post-processing workstation of Siemens for three-dimensional reconstruction and segmentation of the images using the method of range radials. Lastly, the meniscus was measured in the images we segmented. The entire width of meniscus, the width covering the tibia platform of the meniscus and the thickness of the meniscus were measured for quantitative indicators to study.　Results　No significant differences was found between the two groups in the entire width of medial meniscus in all directions, whereas, the width covering the tibia platform of the meniscus from 60° to 120° was smaller in OA than in non-OA knees (P＜0.05) and the thickness of the medial meniscus from 60 °to 130 ° was thicker in OA than in non-OA knees (P＜0.05). There were significant differences in measurement of the lateral meniscus between the two groups. The entire width and the width covering the tibia platform of lateral meniscus from 10° to 50° and 10° to 50° were greater in OA than in non-OA knees (P＜0.05) and the thickness of the lateral meniscus from 120° to 170° were thicker in OA than in non-OA knees (P＜0.05).  Conclusions　The study provides a new check method and train of thought for display and diagnosis of the meniscus with MRI. It is found that the morphology and positions of the meniscus in patients with osteoarthritis have changed and this changes are associated with knee osteoarthritis.