目的　探讨唇裂红唇的形态学特点，为手术治疗提供实验依据。  方法　观测48例唇裂患者红唇外观形态特征，HE染色观察干湿性红唇组织结构。  结果　①Ⅲ度单侧唇裂患侧红唇最厚点厚度为（3.48±0.41）mm，明显小于Ⅱ度唇裂（P<0.05）； ② 双侧唇裂前唇上部宽度明显小于下部，前唇正中的厚度明显大于左右侧（P<0.05）； ③干性红唇上皮棘层和固有层较薄，毛细血管丰富，粘膜下层厚且有大量腺体，肌层较致密；湿性红唇固有层毛细血管少，粘膜下层较薄，腺体少，肌层疏松。  结论　单侧唇裂患侧红唇厚度可能与裂隙大小有关，双侧唇裂前唇外观形态与左右侧有差异，唇裂干湿性红唇组织结构存在明显差异，术中应加以注意。

Objective　To explore the vermilion morphological features of a cleft lip, and to provide the evidence for surgery.     Methods   vermilion features of 48 children with cleft lip patients were observed. HE staining was used to observe the organizational structure of dry or wet vermilions.    Results    （1）The thichestvermilion thickness in injured side was (3.48±0.41) mm of Ⅲ degrees unilateral cleft lip, lower than that in Ⅱ degrees（P<0.05）（2）The front lip width of upper part  was significantly smaller than the lower in bilateral cleft and the thickness in the middle of the front lip was larger than that of the left and right sides（P<0.05）.（3）Epithelial spines layer and inherent layer were thin, the capillary was rich, the submucosal layer was with large glands and the muscle layer was relatively dense in dry vermilion; the capillary in lamina propria layer was sparser submucosal glands were smaller in amount and the muscle layer was  loose in wet vermilion.    Conclusion    The vermilion thickness may correlate with the fissure size in unilateral cleft lip; the front lips were different in shape in the left and right sides in bilateral cleft lip; obvious difference in organization structure exists in dry or wet vermilion in cleft lip, suggesting that the operation should be dealt with caution.