Chinese Journal of Clinical Anatomy >
Reconstruction and volume measurement research and value of cerebellar nuclei based on Amira 5.4
Received date: 2014-05-17
Online published: 2014-12-04
Objective To reconstruct the 3-D visualization model of cerebellar nuclei, and measure the volumes of them for defining the differences of the volumes of cerebellar nuclei between male and female, further providing reliable data for the researches about location, clinical function, and gender differences of cerebellar nuclei. Methods 12 groups of images were obtained from cerebellum specimens embedded by celloidin. Amira 5.4 was used to accomplish 3-D reconstruction and volume measurement of cerebellar nuclei, and then compared the volume of cerebellar nuclei between left and right, male and female. Results 3-D model showed that the structures and morphology of cerebellar nuclei were well-defined; the spatial relationship with the fourth ventricle was also displayed clearly. Regarding the volumes of cerebellar nuclei, we found no differences between the left and right by statistical comparison (P>0.05); a significant statistical difference was found in dentate nucleus between male and female (P<0.001), but for other cerebellar nuclei, there was no significant statistical difference (P>0.05). Conclusion The morphology, volumes of cerebellar nuclei and the spatial relationship with the fourth ventricle can be obtained explicitly by 3-D reconstruction; gender differences of the volumes of dentate nucleus also may provide important value for further function research of cerebellar nuclei.
Key words： Amira; Cerebellar nuclei; Volume measurement; Celloidin
ZHANG Xiao-Yang , WANG Chan-Chan , YUAN Wu , LI Yun-Sheng . Reconstruction and volume measurement research and value of cerebellar nuclei based on Amira 5.4[J]. Chinese Journal of Clinical Anatomy, 2014 , 32(6) : 666 -670 . DOI: 10.13418/j.issn.1001-165x.2014
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