Chinese Journal of Clinical Anatomy >
Pathological features of urethral materials for urethroplasty
Received date: 2014-02-20
Online published: 2014-06-04
Objective To observe the pathological features of urethral materials for urethroplasty and provide guidance for the selection of urethroplasty materials. Methods From September 2011 to October 2013 in Pediatric Surgery of the First Affiliated Hospital of Sun Yat-sen University, 20 cases of proximal hypospadias were corrected for ventral curvature. During the operation, specimen including prepuce, ventral penile skin, scrotal septal skin and scrotal skin were collected, fixed and embedded in paraffin. Then tissues were cut into thin slices, followed by Masson staining and observation under the microscope. 5 HPF were photographed randomly by blinded researchers, then the density of hair follicles, sebaceous glands and vessel as well as the thickness of the skin were measured and calculated. Results Comparison of the density of hair follicles and sebaceous glands: scrotal septal skin < scrotal skin (P＜0.05), while no hair follicles and sebaceous glands were found in the prepuce and ventral penile skin. Comparison of vessel density: prepuce > ventral penile skin > scrotal septal skin > scrotal skin (P＜0.05). Comparison of skin thickness: prepuce < scrotal skin < ventral penile skin < scrotal septal skin (P＜0.05). Conclusions Prepuce and ventral penis skin are ideal candidates for urethroplasty, while the scrotal septal skin can be utilized when the Urethral material is insufficient. Scrotal skin is generally not recommended in urethroplasty.
Key words： Hypospadias; Urethral materials; Masson stainning
XIE Qi-Gen , SU Cheng , LI Zuo-Jing , XU Zhe , SUN Dun-Jie , ZHOU Li . Pathological features of urethral materials for urethroplasty[J]. Chinese Journal of Clinical Anatomy, 2014 , 32(3) : 340 -342 . DOI: 10.13418/j.issn.1001-165x.2014
[1] 施诚仁，金先庆，李仲智，等.小儿外科学
[M].北京：人民卫生出版社，2010：398-402.
[2] 徐哲，张志崇，苏诚，等.游离包皮内板尿道成形术治疗尿道下裂
[J].中山大学学报(医学科学版)，2009，30（5):577-580.
[3] Duckett JW. Transverse preputial island flap technique for repair of severe hypospadias
[J]．Urol Clin North Am，1980，7(2): 423-430．
[4] Ca?r? Sava? M1, Kapucuo?lu N, Gürsoy K, et al. The microvessel density of the hypospadiac prepuce in children
[J]. J Pediatr Urol，2011，7(2):162-165.
[5] Rigamonti W， Castagnetti M. Onlay on albuginea: modified onlay preputial island flap urethroplasty for single-stage repair of primary severe hypospadias requiring urethral plate division
[J]. Urology, 2011, 77(6): 1498-1502.
[6] Hayashi Y, Mizuno K, Kojima Y, et al.Characterization of the urethral plate and the underlying tissue defined by expression of collagen subtypes and microarchitecture in hypospadias
[J]. Int J Urol, 2011, 18:317-322.
[7] Acimi S. Proximal hypospadias: effect of urethral plate mobilization on release of chordee
[J]. Urology, 2012, 80(4): 894-898.
[8] Springer A，Krois W， Horcher E. Trends in hypospadias surgery: results of a worldwide survey
[J]. Eur Urol，2011, 60(6): 1184-1189.
[9] Stehr M，Lehne M， Schuster T，et al. Tubularized incised plate (TIP) urethroplasty (Snodgrass) in primary hypospadias repair
[J]. Eur J Pediatr Surg, 2005, 15(6): 420-423.
[10]Riccabona M.Correction of hypospadias by the Snodgrass method. Indications and results
[J]. Urologe A，2007，46(12):1664-1669.
[11] Mosharafa AA1, Agbo-Panzo D, Priso R,et al. Repair of hypospadias: the effect of urethral plate configuration on the outcome of Duplay-Snodgrass repair
[J]. Prog Urol, 2009, 19(7): 507-510.
[12]黄鲁刚,陈绍基,王明和.阴囊正中带蒂皮瓣尿道下裂修术远期疗效
[J].泌尿外科杂志，1999, 14(2): 215-217.
[13]林煌，李森恺.自体异位尿道再造材料的生物学特性及其在尿道下裂修复手术中应用研究
[D]. 博士论文.中国协和医科大学, 97. 2005.
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