Clinical application study of Nano-Hydroxyapatite artificial bone in bone defect repair

  • WANG Da-Beng ,
  • XIONG Jian-Xi ,
  • SHU Wei-Min ,
  • HUANG Jiang-Hong ,
  • DUAN Chi ,
  • CHEN Ji-Lin ,
  • ZHANG Ju-Feng
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  • 1. Department of Traumatic Orthopedics, Shenzhen Second People’s Hospital, Shenzhen Guangdong 518035; 2. Shenzhen Tissue Engineering Laboratory, Shenzhen 518000, China

Received date: 2013-06-10

  Online published: 2014-04-21

Abstract

Objective To study the clinical effect of nano-hydroxyapatite(Nano-HA) artificial bone on repairing bone defects. Methods From Sep. 2009 to Jun. 2012, 27 cases of bone defect were collected retrospectively. The bone defect ranged from 0.3cm×1.0cm to 3cm×6.5cm, which including the bone defects of humerus, radius, ulna, femur, tibia, and calcaneus. Among them, 22 cases suffered from fractures and 5 cases tumors. All patients were treated with Nano-HA artificial bone. Observation was applied on healing of wounds and X-ray exams preoperatively and postoperatively. Results The patients were followed up from 11 month to 26 months (averagely 18.5 months). X-ray photo showed an integrity interface between Nano-HA and bone. Primary healing was obtained in all cases without any complication. Conclusions The Nano-HA artificial bone has a good biocompatibility. It may be an ideal artificial material to reconstruct bone defect.

Cite this article

WANG Da-Beng , XIONG Jian-Xi , SHU Wei-Min , HUANG Jiang-Hong , DUAN Chi , CHEN Ji-Lin , ZHANG Ju-Feng . Clinical application study of Nano-Hydroxyapatite artificial bone in bone defect repair[J]. Chinese Journal of Clinical Anatomy, 2014 , 32(2) : 206 -209 . DOI: 10.13418/j.issn.1001-165x.2014

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