Research for modification of intracavernous pressure monitoring in establishing rat model with diabetic erectile dysfunction
TUN Zi-Yun, HE Shu-Hua, ZHANG Chao, LIU Lu-Gao, HUI An-Yang
Chinese Journal of Clinical Anatomy ›› 2013, Vol. 31 ›› Issue (2) : 192-195.
Research for modification of intracavernous pressure monitoring in establishing rat model with diabetic erectile dysfunction
Objective To evaluate the modified method of intracavernous pressure(ICP) monitoring in establishing rat model with diabetic erectile dysfunction. Methods Forty male rats were randomized equally into 2 groups (control group and diabetic group). ICP and arterial pressure (AP) were monitored with the improved method and the traditional method, respectively. The modified method used improved intravenous infusion needle puncture in the crus of penis. Results There was no significant difference in measurement of the ICP and AP between the modified method and the traditional method（P＞0.05）, both in the control group and diabetic group. The modified method used improved intravenous infusion needle puncture in the crus of penis can improve the success rate significantly (the traditional method being 75% and the modified method being 100%). Conclusion The modified method of intracavernous pressure monitoring has characteristic of stable、accurate、higher success rate. It is of great significance for establishing rat model with diabetic erectile dysfunction and evaluating rat penile erectile function.
Modification / Intracavernous pressure / Method / Erectile dysfunction / Diabetic
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