Fabrication of niobium-based biological materials via impregnation and its properties
XIONG Jian-Xi, OU Yang-Jian-An, WANG Da-Beng, RUAN Jian-Meng, SHU Wei-Min, BI Zhi-Jiang, ZHANG Hong
Chinese Journal of Clinical Anatomy ›› 2013, Vol. 31 ›› Issue (1) : 89-94.
Fabrication of niobium-based biological materials via impregnation and its properties
Objective to fabricate porous niobium and evaluate its properties. Methods Novel preparation of Polyurethane foam impregnated with niobium powders was used to fabricate the niobium-based materials, which have high strength and excellent biocompatibility. Analytical balance, XRD ，CS600carbon and sulfur analyzer and SEM were used to characterize its porosity, properties and microstructure. Cell biology techniques were used to evaluate the biocompatibility of porous niobium. Results There were three-dimensional, connected pore structure and pure phase in the porous niobium-based materials prepared by solid phase sintering. The porosity, pore size and average density was 71.4%, 500 μm and 2.45 g/cm3, respectively. The elastic modulus and compressive strength of three-dimensional connected porous Nb coincided with cancellous bone in mechanical properties. Porous niobium was suitable for the adhesion, growth and differentiation of osteoblasts. Conclusions Porous niobium possessed high porosity structure, good mechanical properties and biocompatibility.
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