Objective　To explore the value of three-dimensional ultrasonographic diagnosis on the fetal facial rarely abnormalities.　Methods　In 11300 pregnant women of 16～37 gestational weeks from March 2011 to March 2012, the fetal faces were regularly imaged by three-dimensional ultrasonography.　Results　34 cases with facial deformity were detected in all cases, with the detection rate of 0.3%. for those cases, 3 were congenital cataract, 7  microphthalmus, 11 single nostriland, 3 arrhinia,3 parasitus in oral cavity, 1 facial salivary gland cytoma,5 deformity of external ear, 1 anophthalmia. The detection results were finally confirmed by odinopoeia or birth.　Conclusions　Three-dimensional ultrasonography can directly display the fetal facial structures, and is the first choice in the diagnosis of fetal facial abnormalities. Prenatal regular ultrasound has important clinical significance.