Objective　To reconstruct the three-dimensional models of anatomical duct casting specimens. Methods　The anatomic casting models of a lung along with a trachea, artery and vein, and a leg along with bone artery were harvested and scanned by CT scan. The CT data were imported into the software Mimics to reconstruct the three-dimensional models of every part of the anatomic casting models using the function "Threshold", "Edit", "Region growth", etc.　Results　The three-dimensional models of casting specimens of lung and leg were well reconstructed. The detailed structures, such as artery, vein and trachea of casting specimen of lung, arteries of casting specimen of leg could be clearly shown.　Conclusions　The three-dimensional reconstruction can help the anatomical casting specimens to be more useful for medical study and work. Further these three-dimensional reconstructed models can be used to rapid prototype production and other digital medical research.