Objective　To explore Multi-slice spiral CT Isotropic Scanning features of the pterygopalatine fossa （PPF）and its communications，the method of reconstruction by multiplanar reformation (MPR)， study the  Clinical value.  Method　Multi-slice spira CT images of Siemens 16 were performed in 100 adult patients for paranasal sinusitis without abnormality in PPF communications．All original images were transferred to workstation for image processing．According to the shape and appearance of the PPF communications，the best depictive multiplanar reformation(MPR)、maximum intensity projection(MIP)、volume rendering(VR) images were acquired for study.To observe the structure of the pterygopalatine fossa and the channel.  Results　The visualization rates of the foramen rotundum，the  pterygoid canal ，the sphenopalatine foramen，the pterygopalatine canal，the palatovaginal canal and the vomerovaginal canal were 99%、98%、99%、96%、96% and 85% respectively.  Conclusion　Images of Multi-slice spiral CT could accurately demonstrate the shape of the PPF communications and their adjacent structures，and provide scientific and objective foundation for early detection and the formulation of clinical treatment programs.