Objective: To explore anatomic features and variations of intrahepatic portal vein adoting multi-slice CT. Methods: Enhancement scanning CT data of the portal and hepatic venous systems from 200 healthy volunteers were analyzed and classified according to their anatomic features, while, the parameters of portal system were analyzed quantitatively. Results：For all patients examined, the intrahepatic portal vein system of 163 patients (81.5 %) distributed normally, of 23 (11.5 %) , 13 (6.5 %) and 1 (0.5 %) appeared Ⅰ, Ⅱ and Ⅲ types of anatomic variations respectively, however, the absence of the horizontal segment of the left portal vein or right portal vein was not be observed. Dpv, Dsv and Dsmv had significant difference（P<0.05）between male and females. Conclusions：The anatomy and variations of the hepatic portal veins can be easily recognized under multi-slice CT portography(MSCTP).