Objective To investigate the clinical value of diffusion kurtosis imaging (DKI) in assessing early degenerative injury of anterior cruciate ligament (ACL). Methods Fifty unilateral knees of patients underwent DKI scan were collected prospectively from January 2021 to March 2022. They were divided into a normal group (n=25) and a degeneration group (n=25) according to the results of arthroscopy examination. The differences of mean kurtosis (MK), axial kurtosis (AK), radial kurtosis (RK), mean diffusion (MD) and fractional anisotropy (FA) of ACL between two groups were compared. Results The MK value, AK value, RK value and FA value in the degeneration group were lower than those in the normal group significantly (t=8.132, 5.313, 6.885, 9.035, all P<0.01), while MD value were higher than that of the normal group (t=-5.145, P<0.01). The results of the ROC analysis revealed that the above DKI parameters had diagnostic value for ACL degenerative injury, and MK value had the highest diagnostic efficiency. When MK value was 0.884, its diagnostic efficiency was the highest. The sensitivity, specificity, Youden index and area under the ROC curve were 92%, 96%, 0.88 and 0.979, respectively. Conclusions Diffusion kurtosis imaging can quantitatively evaluate early degenerative injury of ACL, which providing reference for clinical evaluation of ACL physiological degeneration.
Key words
Anterior cruciate ligament /
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Injury /
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Diffusion kurtosis imaging /
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Magnetic resonance imaging
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