Objective To investigate the clinical efficacy and sagittal balance changes of a 3D-printed interbody fusion cage in the treatment of single-level cervical spondylosis during anterior cervical discectomy and fusion (ACDF). Methods Retrospective analysis of 60 patients with cervical spondylosis who underwent single-segment ACDF operation in our hospital from June 2017 to June 2019 was performed, thereinto, the experimental group consisted of 30 patients with 3D printed titanium interbody fusion apparatus, the control group was 30 patients treated with polyether ether ketone (PEEK) interbody fusion cage. Related indexes, average length of stay, VAS score at each follow-up period, JOA score and related image parameters, evaluation of curative effect and sagittal balance changes during surgery in the two groups were recorded. Results The operative time of the experimental group was (76.1±5.7) min and the intraoperative blood loss was (33.7±6.5) ml, both of which were lower than the control group ((85.5±6.5) min and (45.3±5.8) mL), the difference was statistically significant (P<0.05). Preoperative JOA and VAS scores of two groups were (4.8±2.3) points, (7.7±1.5) points and (5.1±2.1) points, (8.0±1.6) points respectively. The last postoperative follow-up JOA and VAS scores of two groups were (15.5±1.3) points, (1.0±0.6) points and (14.3±1.5) points, (1.8±0.7) points, respectively, the two scores were significantly improved compared with those before surgery, and the differences were statistically significant (P<0.05). Between groups, the last follow-up data showed statistical difference (P<0.05). There was no significant difference in comparison of preoperative imaging parameters between the two groups (P>0.05). Compared with the group before operation, the postoperative image parameters of each period were significantly improved (P<0.05). At the last follow-up, intervertebral height and angle, C2-7 Cobb angle and T1 inclination angle between experimental group and control group were (6.8±1.3, 5.7±1.4) mm, (7.3±1.3, 6.0±1.4) °, (23.6±5.3, 19.3±5.4) ° and (24.3±2.2, 20.3±2.6) °, respectively. The experimental group was significantly higher than that of the control group, the difference was statistically significant (P<0.05). Conclusions The application of 3D printed titanium alloy interbody fusion cage in the treatment of single level cervical spondylosis in ACDF has a good clinical effect. It is superior to the traditional PEEK fusion cage in improving and maintaining intervertebral height and angle, cervical sagittal balance and other aspects.
Key words
Cervical spondylosis; /
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Anterior cervical discectomy fusion; /
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3D printing; /
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Intervertebral fusion cage
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