Objective To investigate the effect of oblique lateral interbody fusion (OLIF) in the treatment of degenerative lumbar spinal stenosis (DLSS). Methods A total of 103 DLSS patients in our hospital were selected. According to the treatment method, they were divided into an OLIF group (n=51, OLIF operation), a posterior lumbar intervertebral fusion (PLIF) group (n=52, PLIF operation). The curative effect, surgical conditions and perioperative serum inflammatory factors, oxidative stress indicators, spinal cord function, the Visual Analogue Scale (VAS), the Japanese Orthopedic Association (JOA) were compared between the two groups. Results The perioperative index and the effect of 1 year after operation in the OLIF group were better than those in the PLIF group (P<0.05). The levels of serum inflammatory factors in the OLIF group were lower than those in the PLIF group at 1 day and 3 days after operation (P<0.05). The levels of serum advanced oxidation protein products (AOPP) and malondialdehyde (MDA) in the OLIF group were lower than those in the PLIF group at 1 and 3 days after the operation, and the superoxide dismutase (SOD) level was higher than that in the PLIF group (P<0.05). The nerve conduction velocity (NCV) level and JOA score of the tibial nerve and common peroneal nerve in the OLIF group were higher than those in the PLIF group at 6 months and 1 year after the operation, while the latency (DL) and the VAS scores of waist and leg pain were lower than those of the PLIF group (P<0.05). Conclusions OLIF is effective in the treatment of DLSS, with less trauma.
Key words
Oblique lateral interbody fusion; /
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Posterior lumbar intervertebral fusion; /
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Inflammatory factors; /
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Oxidative stress
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