Experimental study on the treatment of distal ureteral obstruction by magnetic compression technique 

Deng Bo, Xu Shuqin, Wang Fangzhou, Shi Yuhang, Li Yixing, Lin Yi, Fan Qian, Ji Lin, Chen Wenwen, Lv Yi, Yan Xiaopeng

Chinese Journal of Clinical Anatomy ›› 2021, Vol. 39 ›› Issue (3) : 319-322.

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Chinese Journal of Clinical Anatomy ›› 2021, Vol. 39 ›› Issue (3) : 319-322. DOI: 10.13418/j.issn.1001-165x.2021.03.013

Experimental study on the treatment of distal ureteral obstruction by magnetic compression technique 

  • Deng Bo1,2,3, Xu Shuqin2,3, Wang Fangzhou2,4, Shi Yuhang2,4, Li Yixing2,4, Lin Yi2,4, Fan Qian2,4, Ji Lin2,4, Chen Wenwen2,4, Lv Yi1,2, Yan Xiaopeng1,2
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Abstract

Objective To explore the feasibility of using magnetic compression technique to treat distal ureteral obstruction. Methods Six New Zealand rabbits were ligated to the distal ureter of the right ureter with silk thread to simulate the model of distal ureteral obstruction after kidney transplantation. After 4 weeks, the ureteral dilatation was observed by laparotomy. It was confirmed that the model was successfully prepared when the ureter dilatation was 5 mm or more. The ureter was cut longitudinally about 5 mm in the upper ureter, where the daughter magnet was placed, and the daughter magnet was slowly pushed to the distal end of the ureter with a soft catheter. Another side, the body of bladder was opened and the incision was stitched by purse-string suture. The incision was about 5 mm long. The parent magnet was placed through the bladder incision, and the parent magnet was pushed to approach the daughter magnet. The parent and daughter magnets could be automatically aligned to absorb and compress the ureter and bladder wall. After a period time of operation, the daughter and parent magnets were detached into the bladder, and the ureter-bladder anastomosis was established. Specimens were obtained and the gross specimens of the anastomosis were observed with naked eyes. Results All the experimental animals were successfully operated and survived well after surgery. After 9-16 days, the daughter and parent magnets were detached into the bladder, and the ureter-bladder anastomosis was established. Obtaining anastomotic specimen showed that the anastomosis healed well. Conclusions Magnetic compression technique (MCT) is safe and feasible for the treatment of distal ureteral obstruction, which can be used clinically to treat distal ureteral obstruction after kidney transplantation.

Key words

Magnetic compression technique /  Magnetosurgery /  Kidney transplantation /  Ureteral obstruction /  Rabbits

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Deng Bo, Xu Shuqin, Wang Fangzhou, Shi Yuhang, Li Yixing, Lin Yi, Fan Qian, Ji Lin, Chen Wenwen, Lv Yi, Yan Xiaopeng. Experimental study on the treatment of distal ureteral obstruction by magnetic compression technique [J]. Chinese Journal of Clinical Anatomy. 2021, 39(3): 319-322 https://doi.org/10.13418/j.issn.1001-165x.2021.03.013

References

[1]  Nie ZL, Li QS, Jin FS, et al. Urological complications in 1223 kidney transplantations[J]. Zhonghua Yi Xue Za Zhi, 2009, 89(18): 1269-1271. PMID: 19595183.
[2] Kwong J, Schiefer D, Aboalsamh G, et al. Optimal management of distal ureteric strictures following renal transplantation: a systematic review[J]. Transpl Int, 2016, 29(5): 579-588. DOI: 10.1111/tri.12759.
[3] Choi YS, Kim KS, Choi SW, et al. Ureteral complications in kidney transplantation: analysis and management of 853 consecutive laparoscopic living-donor nephrectomies in a single center[J]. Transplant Proc, 2016, 48(8): 2684-2688. DOI: 10.1016/j.transproceed.2016.06.054.
[4]  门同义, 张晓明, 王建宁, 等. 肾移植术后长段输尿管狭窄的诊断与开放性手术治疗[J]. 中华器官移植杂志, 2010, 31(8): 485-487. DOI: 10.3760/cma.j.issn.0254-1785.2010.08.011.
[5]  严小鹏, 商澎, 史爱华, 等. 磁外科学体系的探索与建立[J]. 科学通报, 2019, 64(8): 815-826.
[6] Fan C, Zhang HK, Yan XP, et al. Advanced Roux-en-Y hepaticojejunostomy with magnetic compressive anastomats in obstructive jaundice dog models[J]. Surg Endosc, 2018, 32(2): 779-789. DOI: 10.1007/s00464-017-5740-5.
[7]  Ma F, Ma J, Ma SJ, et al. A novel magnetic compression technique for small intestinal end-to-side anastomosis in rats[J]. J Pediatr Surg, 2019, 54(4): 744-749. DOI: 10.1016/j.jpedsurg.2018.07.011.
[8]  An YF, Zhang YC, Liu H, et al. Gastrojejunal anastomosis in rats using the magnetic compression technique[J]. Sci Rep, 2018, 8(1): 11620. DOI: 10.1038/s41598-018-30075-8.
[9]  Wang HH, Ma J, Wang SP, et al. Magnetic anastomosis rings to create portacaval shunt in a canine model of portal hypertension[J]. J Gastrointest Surg, 2019, 23: 2184-2192. DOI: 10.1007/s11605-018-3888-5.
[10]付珊, 马佳, 赵广宾, 等. 磁压榨直肠阴道瘘闭合修补装置的改良设计[J]. 中国医疗设备, 2018, 33(4): 46-49. 
[11]严小鹏, 高燕凤, 邹余粮, 等. 基于磁压榨技术的直肠阴道瘘一期修补装置[J]. 生物医学工程学杂志, 2015, 32(5): 1096-1099. CNKI: SUN:SWGC.0.2015-05-027.
[12]高慧敏, 邱明龙, 张砚超, 等. 磁压榨超微创技术建立兔获得性气管食管瘘动物模型[J]. 中国临床解剖学杂志, 2019, 37(2): 223-227. DOI: 10.13418/j.issn.1001-165x.2019.02.022.
[13]Gao Y, Wu RQ,Lv Y, et al. Novel magnetic compression technique for establishment of a canine model of tracheoesophageal fistula[J]. World J Gastroenterol, 2019, 25(30): 4213-4221. DOI: 10.3748/wjg.v25.i30.4213.
[14]严小鹏, 刘雯雁, 李涤尘, 等. 消化外科手术的内镜化途径: 磁吻合联合内镜[J]. 世界华人消化杂志, 2014, 22(19): 2716-2721. CNKI: SUN:XXHB.0.2014-19-010.
[15]严小鹏, 吕毅, 史爱华, 等. 磁压榨技术治疗复杂性胆道狭窄的临床应用探索[J]. 中华肝胆外科杂志, 2019, 25(3): 237-240.
[16]Ellebaek MBB, Qvist N, Rasmussen L. Magnetic compression anastomosis in long-gap esophageal atresia gross type A: a case report[J]. European J Pediatr Surg Rep, 2018, 6: e37-e39. DOI: 10.1055/s-0038-1649489.
[17]单丽宇, 吕毅, 严小鹏, 等. 基于磁压榨技术的先天性肛门闭锁再通吻合装置的设计[J]. 中国医疗设备, 2019, 24(3): 12-14. CNKI: SUN:YLSX.0.2019-03-005.
[18]邱明龙, 高慧敏, 叶丹, 等. 磁体差异性结构设计在磁压榨技术中的应用分析[J].中国医疗设备, 2019, 34(3): 1-4. CNKI: SUN:YLSX. 0.2019- 03-002.
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