Research on the reference values for ultrasonography of peripheral nerves and cervical nerve roots

Liu Li , Ye Yuqin, Qi Yajie, Wang Cuicui, Xing Yingqi

Chinese Journal of Clinical Anatomy ›› 2021, Vol. 39 ›› Issue (3) : 276-281.

PDF(3160 KB)
PDF(3160 KB)
Chinese Journal of Clinical Anatomy ›› 2021, Vol. 39 ›› Issue (3) : 276-281. DOI: 10.13418/j.issn.1001-165x.2021.03.006

Research on the reference values for ultrasonography of peripheral nerves and cervical nerve roots

  • Liu Li 1,3, Ye Yuqin2, Qi Yajie2, Wang Cuicui2, Xing Yingqi1,2
Author information +
History +

Abstract

Objective To determine normal reference values for cross sectional area (CSA) and the correlation between demographic factors and CSA in the peripheral nerves and cervical roots using ultrasonography. Methods High-resolution ultrasonography of median, ulnar, tibial, fibular, C5, C6 nerves roots of one hundred healthy volunteers were explored. The CSA was measured and each measurement points was repeated for 3 times, and the average value was taken. The correlation between nerve CSA and age, height, weight and body mass index was evaluated. Results Bilateral nerve CSA tended to be symmetrical, with male nerve CSA larger than female nerve CSA. The peripheral nerves of the limbs were positively correlated with height, weight and body mass index, among which the correlation with body weight was the most significant. The CSA in mid-forearm of ulnar nerve, tibial nerve, C5 and C6 nerves root were positively correlated with age. There was no correlation between the difference of bilateral measurement sites and the above demographic characteristics. Conclusions This study provides normative values of CSA in the peripheral nerve roots of the limb and neck, which can be used as the reference criteria for the diagnosis of peripheral nervous diseases.

Key words

High-resolution ultrasonography /  Peripheral nerve /  Nerve root /  Cross sectional area

Cite this article

Download Citations
Liu Li , Ye Yuqin, Qi Yajie, Wang Cuicui, Xing Yingqi. Research on the reference values for ultrasonography of peripheral nerves and cervical nerve roots[J]. Chinese Journal of Clinical Anatomy. 2021, 39(3): 276-281 https://doi.org/10.13418/j.issn.1001-165x.2021.03.006

References

[1]  Devi MA, Meena A. Role of ultrasonography in evaluation of peripheral nerves[J]. Open Journal of Internal Medicine, 2018, 8(4): 232-247.DOI: 10.4236/ojim.2018.84022.
[2]  Winter N, Dammeier N, Schäffer E, et al. Nerve ultrasonography as an additive tool to clinical examination and electrodiagnostics in sporadic mononeuritis-imaging is the key[J]. Ultraschall Med, 2019, 40(4):465-472. DOI: 10.1055/a-0919-4768.
[3]  李亦, 刘明生, 崔丽英. 周围神经病的神经超声研究进展[J]. 中华神经科杂志, 2016, 49(12): 975-979. DOI: 10.3760/cma.j.issn.1006-7876. 2016.12.015.
[4]  俞淼,朱学平,史增元, 等. 正常人腕管内正中神经的超声解剖学研究及其意义[J].中国临床解剖学杂志, 2015, 33(1): 24-27. DOI: 10.13418/j.issn.1001-165x.2015.01.007.
[5] Yalcin E, Onder B, Akyuz M. Ulnar nerve measurements in healthy individuals to obtain reference values[J]. Rheumatol Int, 2013, 33(5): 1143-1147. DOI: 10.1007/s00296-012-2527-9.
[6]  Zaidman CM, Al-Lozi M, Pestronk A. Peripheral nerve size in normals and patients with polyneuropathy: an ultrasound study[J]. Muscle Nerve, 2009, 40(6): 960-966. DOI: 10.1002/mus.21431.
[7]  Noto YI, Shiga K, Tsuji Y, et al. Nerve ultrasound depicts peripheral nerve enlargement in patients with genetically distinct Charcot-Marie-Tooth disease[J]. J Neurol Neursurg Psychiatry, 2015, 86 (4): 378-384. DOI: 10.1136/jnnp-2014-308211.
[8]  Grimm A, Decard BF, Axer H, et al. The Ultrasound pattern sum score - UPSS. A new method to differentiate acute and subacute neuropathies using ultrasound of the peripheral nerves[J]. Clin Neurophysiol, 2015, 126(11): 2216-2225. DOI: 10.1016/j.clinph.2015.01.011.
[9] Won SJ, Kim BJ, Park KS, et al. Reference values for nerve ultrasonography in the upper extremity[J]. Muscle Nerve, 2013, 47(6): 864-871. DOI: 10.1002/mus.23691.
[10]Kerasnoudis A, Pitarokoili K, Behrendt V, et al. Cross sectional area reference values for sonography of peripheral nerves and brachial plexus[J]. Clin Neurophysiol, 2013, 124(9): 1881-1888. DOI: 10.1016/j.clinph.2013.03.007.
[11]Cartwright MS, Passmore LV, Yoon JS, et al. Cross-sectional area reference values for nerve ultrasonography[J]. Muscle Nerve, 2008, 37(5): 566-571. DOI: 10.1002/mus.21009.
[12]Boehm J, Scheidl E, Bereczki D, et al. High-resolution ultrasonography of peripheral nerves: measurements on 14 nerve segments in 56 healthy subjects and reliability assessments[J]. Ultraschall Med, 2014, 35(5): 459-467. DOI: 10.1055/s-0033-1356385.
[13]Qrimli M, Ebadi H, Breiner A, et al. Reference values for ultrasonograpy of peripheral nerves[J]. Muscle nerve, 2016, 53(4): 538-544. DOI: 10.1002/mus.24888.
[14]Seok HY, Jang JH, Won SJ, et al. Cross-sectional area reference values of nerves in the lower extremities using ultrasonography[J]. Muscle nerve, 2014, 50(4): 564-570. DOI: 10.1002/mus.24209.
[15]Bedewi MA, Abodonya A, Kotb M, et al. Estimation of ultrasound reference values for the upper limb peripheral nerves in adults: a cross-sectional study[J]. Medicine (Baltimore), 2017, 96(50) :e9306. DOI: 10.1097/MD.0000000000009306.
[16]Bedewi MA, Abodonya A, Kotb M, et al. Estimation of ultrasound reference values for the lower limb peripheral nerves in adults: a cross-sectional study[J]. Medicine (Baltimore), 2018, 97(12): e0179. DOI: 10.1097/MD.0000000000010179.
[17]Perkins BA, Ngo M, Bril V. Symmetry of nerve conduction studies in different stages of diabetic polyneuropathy[J]. Muscle Nerve, 2002, 25(2): 212-217. DOI: 10.1002/mus.10044.
[18]Tagliafico A, Martinoli C. Reliability of side-to-side sonographic cross-sectional area measurements of upper extremity nerves in healthy volunteers [J]. J Ultrasound Med, 2013, 32(3): 457-462. DOI: 10.7863/jum.2013.32.3.457.
[19]Padua L, Martinoli C, Pazzaglia C, et al. Intra- and internerve cross-sectional area variability: new ultrasound measures[J]. Muscle Nerve, 2012,45(5): 730-733. DOI: 10.1002/mus.23252.
PDF(3160 KB)

Accesses

Citation

Detail

Sections
Recommended

/