Clinical characteristics of dynamic changes of serum creatine kinase in popliteal artery injury in different planes

Mao Jianjie, Gao Jianming

Chinese Journal of Clinical Anatomy ›› 2021, Vol. 39 ›› Issue (2) : 196-201.

PDF(2136 KB)
PDF(2136 KB)
Chinese Journal of Clinical Anatomy ›› 2021, Vol. 39 ›› Issue (2) : 196-201. DOI: 10.13418/j.issn.1001-165x.2021.02.015

Clinical characteristics of dynamic changes of serum creatine kinase in popliteal artery injury in different planes

  • Mao Jianjie1, Gao Jianming1,2
Author information +
History +

Abstract

Objective To investigate the clinical significance about the severity of trauma to the affected limb caused by popliteal artery injury at different levels, to evaluate the role of sural artery in repair of popliteal artery trauma. Methods One hundred and three patients with unilateral knee fracture (dislocation) who were admitted to our hospital from January 2010 to December 2019 were collected. Sixty-eight patients with popliteal artery injury were divided into a high group (n=16) and a low group (n=52) according to whether the injury level was higher than the sural artery or not, the remaining 35 patients were in a control group. The CK (creatine kinase) of three groups before operation and 1 day, 3 days, 7days, 15 days after operation were compared and analyzed. Results CK value in the high group was significantly higher than that in the low group, while the low group was higher than the control group (F=217.709, P<0.001). There were significant differences in CK value among the three groups at the same time point (before operation, 1 day, 3 days, 7 days 15 days after operation) (P<0.001). There were statistical differences in CK value at each time point in the high group (P<0.05); there were no statistical differences in CK value between before operation and 7 days after operation (P=0.930), 1 day and 3 days after operation (P=0.195) in the low group. Conclusions The degree of limb ischemia and injury  in the high group is more serious than that in the low group. The sural artery is the main reason for CK difference at different injury planes of popliteal artery, and it has a compensatory effect.

Key words

Popliteal artery /  Trauma /  Sural artery /  Creatine kinase

Cite this article

Download Citations
Mao Jianjie, Gao Jianming. Clinical characteristics of dynamic changes of serum creatine kinase in popliteal artery injury in different planes[J]. Chinese Journal of Clinical Anatomy. 2021, 39(2): 196-201 https://doi.org/10.13418/j.issn.1001-165x.2021.02.015

References

[1] Guice JL, Gifford SM, Hata K, et al. Analysis of limb outcomes by management of concomitant vein injury in military popliteal artery trauma[J]. Ann Vasc Surg, 2020, 62: 51-56. DOI: 10.1016/j.avsg.2019.05.007.
[2] Keeley J, Koopmann M, Yan H, et al. Factors aAssociated with amputation following popliteal vascular injuries[J]. Ann Vasc Surg, 2015, 29(5): 881-882. DOI: 10.1016/j.avsg.2015.03.030.
[3]  Lang NW, Joestl JB, Platzer P. Characteristics and clinical outcome in patients after popliteal artery injury[J]. J Vasc Surg, 2015, 61(6): 1495-1500. DOI: 10.1016/j.jvs.2015.01.045.
[4]  Ramdass MJ, Muddeen A, Harnarayan P, et al. Risk factors associated with amputation in civilian popliteal artery trauma[J]. Injury, 2018, 49(6): 1188-1192. DOI: 10.1016/j.injury.2018.04.028.
[5]  田小宁, 晁杲, 从飞, 等. 腘血管不同平面损伤的临床意义[J]. 中国矫形外科杂志, 2019, 27(12): 1097-1101. DOI: 10.3977/j.issn.1005-8478.2019.12.09.
[6] Siddiqui MK, Veluchamy A, Maroteau C, et al. CKM Glu83Gly is associated with Blunted creatine kinase variation, but not with myalgia[J]. Circ Cardiovasc Genet, 2017, 10(4): e001737. DOI: 10.1161/CIRCGENETICS.117.001737.
[7]  Deng QY, Tang BH, Xue C, et al. Comparison of the ability to predict mortality between the injury severity score and the new injury severity score: a meta-aAnalysis[J]. Int J Environ Res Public Health, 2016, 13(8): 1-12. DOI: 10.3390/ijerph13080825.
[8] Hohenberger GM, Konstantiniuk P, Cambiaso-Daniel Janos, et al. The mangled extremity severity score fails to be a good predictor for secondary limb amputation after trauma with vascular injury in central europe[J]. World J Surg, 2020, 44(3): 773-779. DOI: 10.1007/s00268-019-05263-w.
[9]  Kumar RS, Singhi PK, Chidambaram M. Are we justified doing salvage or amputation procedure based on mangled extremity severity score in mangled upper extremity injury[J]. J Orthop Case Rep, 2017, 7(1):3-8. DOI: 10.13107/jocr.2250-0685.662.
[10] 梁超, 赵睿, 臧成五, 等. 胶原阵列微管神经支架修复指神经缺损的初步临床研究[J]. 中华手外科杂志, 2019, 35(2): 103-106. DOI: 10.3760/cma.j.issn.l 005-054X.2019.02.008.
[11] Liu CY, Li CD, Wang L, et al. Function scores of different surgeries in the treatment of knee osteoarthritis: a PRISMA-compliant systematic review and network-meta analysis[J]. Medicine (Baltimore), 2018, 97(21): 1-11. DOI: 10.1097/MD.0000000000010828.
[12] Sowards KJ, Mukherjee K, Norris PR, et al. Elevated serum creatine phosphokinase is associated with mortality and inotropic requirement in critically injured adults[J]. Injury, 2014, 45(12): 2096-2100. DOI: 10.1016/j.injury.2014.09.009.
[13] Simpson JP, Taylor A, Sudhan N, et al. Rhabdomyolysis and acute kidney injury: creatine kinase as a prognostic marker and validation of the McMahon Score in a 10-year cohort: a retrospective observational evaluation[J]. Eur J Anaesthesiol, 2016, 33(12): 906-912. DOI: 10.1097/EJA. 0000000000000490.       
[14]Byerly S, Benjamin E, Biswas S, et al. Peak creatinine kinase level is a key adjunct in the evaluation of critically ill trauma patients[J]. Am J Surg, 2017, 214(2): 201-206. DOI: 10.1016/j.amjsurg.2016.11.034.
[15]Keeley J, Koopmann M, Yan H, et al. Factors associated with amputation after popliteal vascular injuries[J]. Ann Vasc Surg, 2016, 33: 83-87. DOI: 10.1016/j.avsg.2016.02.004.
[16]Mullenix PS, Steele SR, Andersen CA, et al. Limb salvage and outcomes among patients with traumatic popliteal vascular injury: an analysis of the National Trauma Data Bank[J]. J Vasc Surg, 2006, 44(1): 94-100. DOI: 10.1016/j.jvs.2006.02.052.
[17] Vasquez CR, Disanto T, Reilly JP, et al. Relationship of body mass index, serum creatine kinase, and acute kidney injury after severe trauma[J]. J Trauma, 2020, 89(1): 179-185. DOI: 10.1097/TA.00000 00000002714.
[18] Patterson BM, Agel J, Swiontkowski MF, et al. Knee dislocations with vascular injury: outcomes in the Lower Extremity Assessment Project (LEAP) Study[J]. J Trauma, 2007, 63(4): 855-858. DOI: 10.1097/TA.0b013e31806915a7.
[19]Talving P, Karamanos E, Skiada D, et al. Relationship of creatine kinase elevation and acute kidney injury in pediatric trauma patients[J]. J Trauma, 2013, 74(3): 912-916. DOI: 10.1097/TA.0b013e318278954e.
PDF(2136 KB)

Accesses

Citation

Detail

Sections
Recommended

/