Objective To study the relationship between the arachnoid granulation (AG) in dural sinus and age. Methods The clinical and imaging data of 360 patients with intracranial no abnormalities were collected according to the age. The distribution of AG in venous sinus and the shape, size, number and the changes of morphology in the same patients of AG in each age group were observed. Results MR examination showed that the most common site of AG was transverse sinus, followed by superior sagittal sinus, straight sinus, torcular, cavernous sinus. With the increasing of age in the juveniles patients group, the AG diameter became larger, the quantity and the number of lobulated of AG gradually increased. With the increasing of age in the middle-aged patients group, the diameter and number fluctuations in the fixed range, the shape remained basically unchanged. There were statistical difference in the number and diameter of patients who could detect AG between the juveniles group and the middle-aged group. With the increasing of age in the old-aged patients group, the AG diameter became small, number and the number of lobulated also reduced. There were statistical difference in the number and diameter of patients who could detect AG between the middle-aged group and the old-aged group. Conclusions The number, size and shape of the arachnoid granulation are variable in different age groups, and these changes may be closely related to growth and development, aging and regulation of cerebrospinal fluid reabsorption.
Key words
Arachnoid granulation /
Magnetic resonance imaging /
Age /
Cerebrospinal fluid /
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] Tsutsumi S, Ogino I, Miyajima M, et al. Cranial arachnoid protrusions and contiguous diploic veins in CSF drainage[J]. AJNR Am J Neuroradiol, 2014, 35(9): 1735-1739.
[2] Watane GV, Patel B, Brown D, et al. The significance of arachnoid granulation in patients with idiopathic intracranial hypertension[J]. J Comput Assist Tomogr, 2018, 42(2): 282-285.
[3] Liebo GB, Lane JJ, Van Gompel JJI, et al. Brain herniation into arachnoid granulations: clinical and neuroimaging features[J]. J Neuroimaging, 2016, 26(6): 592-598.
[4] Gailloud P, Muster M, Khaw N, et al. Anatomic relationship between arachnoid granulations in the transverse sinus and the termination of the vein of labbé: an angiographic study[J]. Neuroradiology, 2001, 43(2): 139-143.
[5] Leach JL, Jones BJ, Tomsick TA, et al. Normal appearance of arachnoid granulations on contrast-enhanced CT and MR of the brain: differentiation from dural sinus disease[J]. AJNR Am J Neuroradiol, 1996, 17(8): 1523-1532.
[6] Roche J, Warner D. Arachnoid granulations in the transverse and sigmoid sinuses: CT, MR, and MR angiographic appearance of a normal anatomic variation[J]. AJNR Am J Neuroradiol 1996, 17(4): 677-683.
[7] 宋海民, 李东海. 颅内蛛网膜与脑池研究进展[J]. 中国临床解剖学杂志, 2015, 33(6): 726-727.
[8] Sade R, Ogul H, Polat G, et al. Brain herniation into the transverse sinuses’ arachnoid granulations in the pediatric population investigated with 3T MRI[J]. Acta Neurol Belg, 2019, 119(2): 225-231.
[9] 罗琳, 鱼博浪, 王泽忠. 蛛网膜颗粒及其影像学表现[J]. 实用放射学杂志, 2001, 17(2): 142-143.
[10]Góomez DG, Dibenedetto AT, Pavese AM, et al. Development of arachnoid villi and granulation in man[J]. Acta Anat (Basel), 1982, 111(3): 247-258.
[11]肖俊强, 卢光明, 程传虎. 静脉窦蛛网膜颗粒CT、MRI表现[J]. 中国临床医学影像杂志, 2012, 23(11): 805-807.
[12] Ikushima I, Korogi Y, Makita O, et al. MRI of arachnoid granulations within the dural sinuses using a FLAIR pulse sequence[J]. Br J Radiol, 1999, 72 (863): 1046-1051.
[13]Liang L, Korogi Y, Sugahara T, et al. Normal structures in the intracranial dural sinuses: delineation with 3D contrast-enhanced magnetization prepared rapid acquisition gradient-echo imaging sequence[J]. AJNR Am J Neuroradiol, 2002, 23(10): 1739-1746.
[14] 孙金龙, 崔庆轲, 张庆林, 等. 国人上矢状窦窦腔内结构的内镜解剖[J]. 中华神经外科杂志, 2006, 22(9): 525-527.
[15] 康晓雨, 黄理金. 上矢状窦及其静脉属支的解剖学研究进展[J]. 中国临床解剖学杂志, 2015, 33(4): 491-493.
[16]Haroun AA, Mahafza WS, Najar MSA. Arachnoid granulations in the cerebral dural sinuses as demonstrated by contrast-enhanced 3D magnetic resonance venography[J]. Surg Radiol Anat, 2007, 29(4): 323-328.
[17]Grossman CB, Potts DG. Arachnoid granulations: radiology and anatomy[J]. Radiology, 1974, 113(1): 95-100.
