Imaging study of regional coordination function of cerebral motor in patients with ischemic stroke

doi:10.13418/j.issn.1001-165x.2020.04.006

Chinese Journal of Clinical Anatomy ›› 2020, Vol. 38 ›› Issue (4) : 391-395. DOI: 10.13418/j.issn.1001-165x.2020.04.006

LI Ding^1,2, WANG Ya^1,2,3, WANG Yan-fang^{1,2, 3}, CHEN Yan-jun³, LI Jing-ming¹, HUANG Wen-hua^1,2

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Abstract

Objective　To evaluate the correlation between craniocerebral neuroanatomy and regional brain function in patients with ischemic stroke, and to further explore the neural mechanism of ischemic stroke.　Methods　15 healthy patients in a control group and 19 patients with upper limb hemiplegia in subacute ischemic stroke were collected. The functional connection index of the internal craniocerebral hemisphere was calculated by using computational neuroimaging, and the clinical rehabilitation score before and after treatment was collected for statistical correlation analysis.　Results　(1) Compared with the control group, cerebral hemispheric functional connectivity significantly reduced in stroke patients, with statistically significant differences (T=-10.077, P<0.001). (2) The abnormal focus of lesions was in the supplementary motor area (P=0.02) and the anterior central gyrus (P=0.03), and the difference was statistically significant. (3) The functional connection value in the anterior central gyrus of the patient group before and after drug treatment was positively correlated with the rehabilitation scoring scale, and the difference was statistically significant (r=0.29, P=0.03).　Conclusions　The decrease of functional connections of hemispheres in cerebral motor areas in patients with subcortical ischemic stroke may provide a new approach for clinical diagnosis and rehabilitation evaluation.

Key words

Ischemic stroke / 　Tomography / 　Functional connectivity / 　Cortical motor area / Rehabilitation score

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LI Ding, WANG Ya, WANG Yan-fang, CHEN Yan-jun, LI Jing-ming, HUANG Wen-hua. Imaging study of regional coordination function of cerebral motor in patients with ischemic stroke[J]. Chinese Journal of Clinical Anatomy. 2020, 38(4): 391-395 https://doi.org/10.13418/j.issn.1001-165x.2020.04.006

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