Effects of dexmedetomidine combined with ropivacaine on anesthesia and stress response in children
QIAN Xing-hua, ZHU Zhi-rui, HU Zhi-yong
Chinese Journal of Clinical Anatomy ›› 2019, Vol. 37 ›› Issue (2) : 213-216.
Effects of dexmedetomidine combined with ropivacaine on anesthesia and stress response in children
Objective To explore the effect of dexmedetomidine combined with ropivacaine on anesthesia in pediatric foreskin surgery and its effect on children's postoperative stress response. Methods A total of 98 cases of pediatric foreskin patients admitted to our hospital from August 2016 to August 2017 were selected as subjects of this study, and randomly divided into two groups with 49 cases each. The control group was treated with ropivacaine anesthesia, and the study group was treated with dexmedetomidine combined with ropivacaine for anesthesia. The analgesic effect, onset time, recovery time, postoperative restlessness rate, stress response and adverse reaction symptoms were compared between the two groups. Results The analgesic effect of the study group was significantly better than that of the control group (P<0.05). Operation time, onset time of anesthesia and postoperative restlessness rate of the study group were significantly lower than those of the control group (P<0.05). Stress indexes such as blood glucose, cortisol and adrenaline concentration in the study group were significantly lower than those in the control group (P<0.05). The adverse reaction rate of the study group was significantly lower than that of the control group (P<0.05). Conclusion The application of dexmedetomidine combined with ropivacaine in pediatric foreskin surgery can effectively reduce the stress response of children. In terms of analgesia and sedation, it provides a relatively safe and convenient analgesic method with few complications, which should be further promoted in clinical application.
Dexmedetomidine / Ropivacaine / Pediatric circumcision / Anesthesia / Effect / Stress response
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