Objective　Investigating the advantages of using double ring areola incision in the clinical operation of multi-center benign breast tumors.　Methods　A retrospective analysis of 45 cases of multic-enter breast benign tumor treated with double ring areola incision in our department of oncology surgery from January 2016 to July 2017 was conducted. The clinical and pathological factors, operative time, intraoperative blood loss, extubation time, complications and cosmetic result after 3 months, the recurrence rate after 6 months were evaluated.　Result　The number of resected tumor in unilateral sidewas 5±1 (2~8), in bilateral sides was 8±2 (3~13). Tumor size in unilateral side was(5.3±1.3) cm (1.5~8.5 cm), in bilateral sides was(3±1.5) cm (1.2~6.5 cm). The amount of intraoperative bleeding in unilateral was(8±2.8) ml (5~15ml), in bilateral sides was(15.4±3.1)ml (10~25 ml). Cosmetic results were followed up by outpatient and WeChat after 3 months and patients’ satisfaction reached 93.3%. After 6 months, there were 37 patients who underwent Doppler ultrasound examination, including 22 cases of patients with unilateral lesions, in whichtumor in 3 cases of recurred, the recurrence rate in 13.6%; 15 cases of patients with bilateral lesions, in which tumor in 2 cases of recurred, the recurrence rate being 13.3%.　Conclusion　Double ring areola incision has certain advantages in the treatment of patient who has multiple tumors distributed in different quadrants or has shaping demand. The operation is safe and convenient, and suitable for clinical application.