Study of hemodynamics on three different patterns of flaps on dorsum of rats
Chinese Journal of Clinical Anatomy ›› 2016, Vol. 34 ›› Issue (1) : 6-11.
Study of hemodynamics on three different patterns of flaps on dorsum of rats
Objective To study hemodynamic characteristics of three different patterns of flaps on the dorsum of rats. Methods 30 Sprague Dawley rat were equally divided into three groups: the perforator group, the perforator-based fasicocutaneous flap group and the random flap group. Laser Doppler flowmeter was adopted for measurement of blood perfusion on zoneⅠ、Ⅱand Ⅲ of the flaps on the three groups at the multiple time points. 7 d after surgery, photographs were taken for the flaps and the fasciocutaneous vascular network between the iliolumbar perforator and the sacrococcygeal perforator. Comparison of necrotic rates among the three groups, and comparison of perfusion values of zoneⅠ、Ⅱand Ⅲ on the perforator flap and the perforator-based fasciocutaneous flap immediately and 1d after surgery were carried out. Results The necrotic rates of the perforator flap, the perforator-based fasciocutaneous flap and the random flap was 0.087±0.07, 0.071±0.05 and 0.267±0.11, respectively. Immediately after surgery, the perfusion value of zoneⅠandⅡin the perforator flap group was larger than that in the perforator-based fasciocutaneous flap group with statistical significance. Perfusion value of the three zones in the random flap group was lower than their counterparts of the perforator flap group and the perforator-based fasciocutaneous flap. 7 d after surgery, the vascular network between the iliolumbar perforator and the sacrococcygeal perforator underwent tremendous enlargement in diameter. Conclusion There is no significant difference on the survival capacity between the perforator flap and the perforator-based fasciocutaneous flap. The survival of the random flap depends on the dilation of the vascular network between the pedicle and the nearest potential perforator.
Perforator / Fasciocutaneous / Random flap / Laser doppler flowmeter / Hemodynamics
[1] Mehrotra S. Perforator-plus flaps: a new concept[J]. Plast Reconstr Surg, 2007, 119(2):590-598.
[2] Meši? H, Kirkebøen KA, Bains R. The importance of a skin bridge in peripheral tissue perfusion in perforator flaps [J]. Plast Reconstr Surg, 2012 ,129(3):428e-434e.
[3] 孔琚，李哲，秦兴军，等. 随意皮瓣修复眶周软组织缺损的体会 [J]. 中国医科大学学报，2010， 39（2）：144-149.
[4] 孔进，范进文. 鼻唇沟随意皮瓣修复鼻翼部分缺损[J]. 中国美容医学， 2008，17（10）：1462-1463.
[5] 庄跃宏，胡斯旺，吴东方，等. 一种研究choke血管新的动物模型-大鼠背部皮窗 [J]. 中国临床解剖学杂志，2011，29 (6 ) ：609-613.
[6] 张善才，李金明，宋克勤，等. 小腿内侧游离皮瓣的临床应用[J]. 中华外科杂志，1983，21（12）：743-745.
[7] Masquelet AC, Romana MC, Wolf G. Skin island flaps supplied by the vascular axis of the sensitive superficial nerves: anatomic study and clinical experience in the leg [J]. Plast Reconstr Surg, 1992, 89(6):1115-1121.
[8] Kroll SS, Rosenfield L. Perforator-based flaps for low posterior midline defects [J]. Plast Reconstr Surg, 1988, 81(4): 561-566.
[9] 杨大平，唐茂林，Christopher R，等. 皮肤穿支血管的解剖学研究 [J]. 中国临床解剖学杂志，2006，24（2）：232-235.
[10]徐达传，张世民，唐茂林，等. 穿支皮瓣的发展与现状 [J].中国修复重建外科杂志，2011，25（9）：1025-1029.
[11]庄跃宏，梁成，温福利，等. 延迟术通过加强血管扩张的方式促进跨区皮瓣存活[J].中国临床解剖学杂志，2015，33 (1 )：44-50.
[12] Demir A, Acar M, Yldz L, et al. The effect of twisting on perforator flap viability: an experimental study in rats [J]. Ann Plast Surg, 2006, 56(2):186-189.
[13] Chang CH, Lim SY, Pyon JK, et al. The influence of pedicle length on the viability of twisted perforator flaps in rats [J]. J Reconstr Microsurg, 2009, 25(9):533-538.
[14] Wong CH, Cui F, Tan BK, et al. Nonlinear finite element simulations to elucidate the determinants of perforator patency in propeller flaps [J]. Ann Plast Surg, 2007, 59(6):672-678.
[15] 陶友伦，张世民，陈文龙，等. 穿支血管蒂螺旋桨皮瓣蒂部血管扭转的非线性有限元模拟研究 [J]. 中国临床解剖学杂志，2014，32 (2):201-205.
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